Comparing the Outcomes of Patients With Carbapenemase-Producing and Non-Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae Bacteremia

Background. Carbapenem-resistant Enterobacteriaceae (CRE) are associated with considerable mortality. As mechanisms of carbapenem resistance are heterogeneous, it is unclear if mortality differs based on resistance mechanisms. We sought to determine whether CRE resistance mechanism determination is...

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Veröffentlicht in:	Clinical infectious diseases 2017-02, Vol.64 (3), p.257-264
Hauptverfasser:	Tamma, Pranita D., Goodman, Katherine E., Harris, Anthony D., Tekle, Tsigereda, Roberts, Ava, Taiwo, Abimbola, Simner, Patricia J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use ARTICLES AND COMMENTARIES Bacteremia - blood Bacteremia - drug therapy Bacteremia - mortality Bacterial Proteins - genetics Bacterial Proteins - metabolism beta-Lactam Resistance beta-Lactamases - genetics beta-Lactamases - metabolism Carbapenems - pharmacology Carbapenems - therapeutic use Clinical outcomes Cohort Studies Comparative analysis CRE bacteria Deoxyribonucleic acid DNA DNA, Bacterial - genetics DNA, Bacterial - isolation & purification Enterobacteriaceae Enterobacteriaceae - drug effects Enterobacteriaceae - enzymology Enterobacteriaceae - pathogenicity Enterobacteriaceae Infections - blood Enterobacteriaceae Infections - drug therapy Enterobacteriaceae Infections - mortality Female Genes Humans Major Male Meropenem Middle Aged Mortality Retrospective Studies Thienamycins - pharmacology Thienamycins - therapeutic use Treatment Outcome
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