Loss of CTRP1 disrupts glucose and lipid homeostasis

C1q/TNF-related protein 1 (CTRP1) is a conserved plasma protein of the C1q family with notable metabolic and cardiovascular functions. We have previously shown that CTRP1 infusion lowers blood glucose and that transgenic mice with elevated circulating CTRP1 are protected from diet-induced obesity an...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2016-10, Vol.311 (4), p.E678-E697
Hauptverfasser:	Rodriguez, Susana, Lei, Xia, Petersen, Pia S, Tan, Stefanie Y, Little, Hannah C, Wong, G William
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipokines - deficiency Adipokines - genetics AMP-Activated Protein Kinases - metabolism Animals Blood Glucose - metabolism Body Weight - genetics Cholesterol - blood Diet, High-Fat Eating Energy Metabolism - genetics Gluconeogenesis - genetics Glucose Glucose - metabolism Glucose Transporter Type 4 - metabolism Homeostasis Homeostasis - genetics Lipid Metabolism - genetics Lipids Liver - metabolism Mice, Inbred C57BL Mice, Knockout Obesity Obesity - genetics Proteins Rodents Triglycerides - blood
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