Captopril and Valsartan May Improve Cognitive Function Through Potentiation of the Brain Antioxidant Defense System and Attenuation of Oxidative/Nitrosative Damage in STZ-Induced Dementia in Rat

Previous findings have shown the crucial roles of brain renin-angiotensin system (RAS) in pathogenesis of Alzheimer's disease (AD). Since RAS inhibitors may have beneficial effects on dementia and cognitive function in elderly people, the aim of present study was to examine the neuroprotective...

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Veröffentlicht in:Advanced pharmaceutical bulletin 2016-12, Vol.6 (4), p.531-539
Hauptverfasser: Arjmand Abbassi, Yasaman, Mohammadi, Mohammad Taghi, Sarami Foroshani, Mahsa, Raouf Sarshoori, Javad
Format: Artikel
Sprache:eng
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