Growth hormone: a newly identified developmental organizer

The sexually dimorphic expression of cytochromes P450 (CYP) drug-metabolizing enzymes has been reported in all species examined. These sex differences are only expressed during adulthood and are solely regulated by sex differences in circulating growth hormone (GH) profiles. Once established, howeve...

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Veröffentlicht in:	Journal of endocrinology 2017-03, Vol.232 (3), p.377-389
Hauptverfasser:	Das, Rajat K, Banerjee, Sarmistha, Shapiro, Bernard H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aryl Hydrocarbon Hydroxylases - genetics Aryl Hydrocarbon Hydroxylases - metabolism Cytochrome P450 Family 2 - genetics Cytochrome P450 Family 2 - metabolism Drug metabolism Female Gender differences Gene Expression Regulation, Enzymologic - drug effects Growth Hormone - blood Growth Hormone - pharmacology Growth hormones Hepatocytes - drug effects Hepatocytes - metabolism Imprinting Male Rats Rodents Secretion Sex differences Sexual dimorphism Signal transduction Signal Transduction - drug effects Steroid 16-alpha-Hydroxylase - genetics Steroid 16-alpha-Hydroxylase - metabolism Suppressor of Cytokine Signaling Proteins - genetics Suppressor of Cytokine Signaling Proteins - metabolism
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