Differential susceptibility and maturation of thymocyte subsets during Salmonella Typhimurium infection: insights on the roles of glucocorticoids and Interferon-gamma

The thymus is known to atrophy during infections; however, a systematic study of changes in thymocyte subpopulations has not been performed. This aspect was investigated, using multi-color flow cytometry, during oral infection of mice with Salmonella Typhimurium ( S . Typhimurium). The major highlig...

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Veröffentlicht in:	Scientific reports 2017-01, Vol.7 (1), p.40793-40793, Article 40793
Hauptverfasser:	Majumdar, Shamik, Deobagkar-Lele, Mukta, Adiga, Vasista, Raghavan, Abinaya, Wadhwa, Nitin, Ahmed, Syed Moiz, Rananaware, Supriya Rajendra, Chakraborty, Subhashish, Joy, Omana, Nandi, Dipankar
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/31 631/250/255/1318 631/80/82/23 64 64/60 Animals Atrophy Biomarkers CD4 antigen CD8 antigen Cell Differentiation - immunology Color Disease Susceptibility Flow cytometry Glucocorticoids Glucocorticoids - metabolism Humanities and Social Sciences Immunophenotyping Infections Inflammation Interferon-gamma - metabolism Lymphocyte Count Maturation Mice multidisciplinary Oral infection Rodents Salmonella Salmonella Infections - immunology Salmonella Infections - metabolism Salmonella Infections - microbiology Salmonella Infections - pathology Salmonella typhimurium - physiology Science Science (multidisciplinary) Signal Transduction Subpopulations T-Lymphocyte Subsets - cytology T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism Thymocytes Thymocytes - cytology Thymocytes - immunology Thymocytes - metabolism Thymus Thymus Gland - immunology Thymus Gland - metabolism Thymus Gland - pathology
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