Nanoscintillator-Mediated X‑ray Inducible Photodynamic Therapy for In Vivo Cancer Treatment

Photodynamic therapy is a promising treatment method, but its applications are limited by the shallow penetration of visible light. Here, we report a novel X-ray inducible photodynamic therapy (X-PDT) approach that allows PDT to be regulated by X-rays. Upon X-ray irradiation, the integrated nanosyst...

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Veröffentlicht in:	Nano letters 2015-04, Vol.15 (4), p.2249-2256
Hauptverfasser:	Chen, Hongmin, Wang, Geoffrey D, Chuang, Yen-Jun, Zhen, Zipeng, Chen, Xiaoyuan, Biddinger, Paul, Hao, Zhonglin, Liu, Feng, Shen, Baozhong, Pan, Zhengwei, Xie, Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical materials Cancer Cell Survival - drug effects Cell Survival - radiation effects Delayed-Action Preparations - administration & dosage Delayed-Action Preparations - chemistry Delayed-Action Preparations - radiation effects In vivo testing In vivo tests Light Nanocapsules - chemistry Nanocapsules - radiation effects Nanocapsules - ultrastructure Nanostructure Neoplasms, Experimental - drug therapy Neoplasms, Experimental - pathology Photochemotherapy - methods Photodynamic therapy Photons Photosensitizing Agents - administration & dosage Photosensitizing Agents - chemistry Treatment Outcome X-Ray Therapy - methods X-Rays
Online-Zugang:	Volltext
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