Bronchial tree‐shaped mucous plug in cystic fibrosis: imaging‐guided management
We report the case of a 17‐year‐old boy with cystic fibrosis (CF) who presented with persistent cough; after starting intravenous antibiotics for Pseudomonas aeruginosa he underwent a computed tomography (CT) scan of the chest. CT revealed extensive consolidation in the right lower lobe with relativ...
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description | We report the case of a 17‐year‐old boy with cystic fibrosis (CF) who presented with persistent cough; after starting intravenous antibiotics for Pseudomonas aeruginosa he underwent a computed tomography (CT) scan of the chest. CT revealed extensive consolidation in the right lower lobe with relative bronchus obstruction; the cause of bronchial obstruction was detected in the mediastinal window, corresponding to a bronchial tree‐shaped, thick, tenacious mucous plug. This was extracted 48 h after unresponsive bronchial washing and endobronchial instillation of rhDNAse, using foreign‐body forceps, with subsequent resolution of cough. This case, which is the second report of plastic bronchitis in CF, was resolved by mechanical removal of the mucous plug, suggesting that a careful observation of CT imaging may guide intervention aimed at resolution of atelectasis.
This is the second report of plastic bronchitis in cystic fibrosis that resolved with mechanical removal of the mucous plug. A careful observation of computed tomography (CT) imaging may guide intervention aimed at resolution of atelectasis. |
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This is the second report of plastic bronchitis in cystic fibrosis that resolved with mechanical removal of the mucous plug. A careful observation of computed tomography (CT) imaging may guide intervention aimed at resolution of atelectasis.</description><identifier>ISSN: 2051-3380</identifier><identifier>EISSN: 2051-3380</identifier><identifier>DOI: 10.1002/rcr2.214</identifier><identifier>PMID: 28096997</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>Antibiotics ; Atelectasis ; Bronchitis ; Case Report ; Case Reports ; Cystic fibrosis ; DNAse ; Histology ; imaging ; Medical imaging ; Patients ; plug ; Viscosity</subject><ispartof>Respirology case reports, 2017-03, Vol.5 (2), p.e00214-n/a</ispartof><rights>2017 The Authors. published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology</rights><rights>2017. This work is published under http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4334-609012a1c8380e7814fad67231ace7bfbce6ee215f720f7088d45164a7a315573</citedby><cites>FETCH-LOGICAL-c4334-609012a1c8380e7814fad67231ace7bfbce6ee215f720f7088d45164a7a315573</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233562/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233562/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,1416,11561,27923,27924,45573,45574,46051,46475,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28096997$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Salamone, Ignazio</creatorcontrib><creatorcontrib>Mondello, Baldassare</creatorcontrib><creatorcontrib>Lucanto, Maria Cristina</creatorcontrib><creatorcontrib>Cristadoro, Simona</creatorcontrib><creatorcontrib>Lombardo, Mariangela</creatorcontrib><creatorcontrib>Barone, Mario</creatorcontrib><title>Bronchial tree‐shaped mucous plug in cystic fibrosis: imaging‐guided management</title><title>Respirology case reports</title><addtitle>Respirol Case Rep</addtitle><description>We report the case of a 17‐year‐old boy with cystic fibrosis (CF) who presented with persistent cough; after starting intravenous antibiotics for Pseudomonas aeruginosa he underwent a computed tomography (CT) scan of the chest. CT revealed extensive consolidation in the right lower lobe with relative bronchus obstruction; the cause of bronchial obstruction was detected in the mediastinal window, corresponding to a bronchial tree‐shaped, thick, tenacious mucous plug. This was extracted 48 h after unresponsive bronchial washing and endobronchial instillation of rhDNAse, using foreign‐body forceps, with subsequent resolution of cough. This case, which is the second report of plastic bronchitis in CF, was resolved by mechanical removal of the mucous plug, suggesting that a careful observation of CT imaging may guide intervention aimed at resolution of atelectasis.
This is the second report of plastic bronchitis in cystic fibrosis that resolved with mechanical removal of the mucous plug. A careful observation of computed tomography (CT) imaging may guide intervention aimed at resolution of atelectasis.</description><subject>Antibiotics</subject><subject>Atelectasis</subject><subject>Bronchitis</subject><subject>Case Report</subject><subject>Case Reports</subject><subject>Cystic fibrosis</subject><subject>DNAse</subject><subject>Histology</subject><subject>imaging</subject><subject>Medical imaging</subject><subject>Patients</subject><subject>plug</subject><subject>Viscosity</subject><issn>2051-3380</issn><issn>2051-3380</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>WIN</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNp1kctKAzEUhoMoVmrBJ5ABN26m5iSTubgQtHiDglB1HTKZzDRlLjWZUbrzEXxGn8QMraUuXOWQfOc_f86P0AngMWBMLow0ZEwg2ENHBDPwKY3x_k49QCNrFxhjAHcFcIgGJMZJmCTREXq-MU0t51qUXmuU-v78snOxVJlXdbLprLcsu8LTtSdXttXSy3VqGqvtpacrUei6cA1Fp7O-QdSiUJWq22N0kIvSqtHmHKLXu9uXyYM_fbp_nFxPfRlQGvghTjAQATJ2JlUUQ5CLLIwIBSFVlOapVKFSBFgeEZxHOI6zgEEYiEhQYCyiQ3S11l12aaUy6UYbUfKlcd7MijdC878vtZ7zonnnjFDKQuIEzjYCpnnrlG35oulM7TxzQpw5YAkLHXW-pqT7ujUq304AzPsEeJ8Adwk49HTX0Rb83bcD_DXwoUu1-leIzyYz0gv-ABWMka4</recordid><startdate>201703</startdate><enddate>201703</enddate><creator>Salamone, Ignazio</creator><creator>Mondello, Baldassare</creator><creator>Lucanto, Maria Cristina</creator><creator>Cristadoro, Simona</creator><creator>Lombardo, Mariangela</creator><creator>Barone, Mario</creator><general>John Wiley & Sons, Ltd</general><general>John Wiley & Sons, Inc</general><scope>24P</scope><scope>WIN</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>201703</creationdate><title>Bronchial tree‐shaped mucous plug in cystic fibrosis: imaging‐guided management</title><author>Salamone, Ignazio ; Mondello, Baldassare ; Lucanto, Maria Cristina ; Cristadoro, Simona ; Lombardo, Mariangela ; Barone, Mario</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4334-609012a1c8380e7814fad67231ace7bfbce6ee215f720f7088d45164a7a315573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Antibiotics</topic><topic>Atelectasis</topic><topic>Bronchitis</topic><topic>Case Report</topic><topic>Case Reports</topic><topic>Cystic fibrosis</topic><topic>DNAse</topic><topic>Histology</topic><topic>imaging</topic><topic>Medical imaging</topic><topic>Patients</topic><topic>plug</topic><topic>Viscosity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Salamone, Ignazio</creatorcontrib><creatorcontrib>Mondello, Baldassare</creatorcontrib><creatorcontrib>Lucanto, Maria Cristina</creatorcontrib><creatorcontrib>Cristadoro, Simona</creatorcontrib><creatorcontrib>Lombardo, Mariangela</creatorcontrib><creatorcontrib>Barone, Mario</creatorcontrib><collection>Wiley-Blackwell Open Access Titles</collection><collection>Wiley Free Content</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Respirology case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Salamone, Ignazio</au><au>Mondello, Baldassare</au><au>Lucanto, Maria Cristina</au><au>Cristadoro, Simona</au><au>Lombardo, Mariangela</au><au>Barone, Mario</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bronchial tree‐shaped mucous plug in cystic fibrosis: imaging‐guided management</atitle><jtitle>Respirology case reports</jtitle><addtitle>Respirol Case Rep</addtitle><date>2017-03</date><risdate>2017</risdate><volume>5</volume><issue>2</issue><spage>e00214</spage><epage>n/a</epage><pages>e00214-n/a</pages><issn>2051-3380</issn><eissn>2051-3380</eissn><abstract>We report the case of a 17‐year‐old boy with cystic fibrosis (CF) who presented with persistent cough; after starting intravenous antibiotics for Pseudomonas aeruginosa he underwent a computed tomography (CT) scan of the chest. CT revealed extensive consolidation in the right lower lobe with relative bronchus obstruction; the cause of bronchial obstruction was detected in the mediastinal window, corresponding to a bronchial tree‐shaped, thick, tenacious mucous plug. This was extracted 48 h after unresponsive bronchial washing and endobronchial instillation of rhDNAse, using foreign‐body forceps, with subsequent resolution of cough. This case, which is the second report of plastic bronchitis in CF, was resolved by mechanical removal of the mucous plug, suggesting that a careful observation of CT imaging may guide intervention aimed at resolution of atelectasis.
This is the second report of plastic bronchitis in cystic fibrosis that resolved with mechanical removal of the mucous plug. A careful observation of computed tomography (CT) imaging may guide intervention aimed at resolution of atelectasis.</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>28096997</pmid><doi>10.1002/rcr2.214</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Antibiotics Atelectasis Bronchitis Case Report Case Reports Cystic fibrosis DNAse Histology imaging Medical imaging Patients plug Viscosity |
title | Bronchial tree‐shaped mucous plug in cystic fibrosis: imaging‐guided management |
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