Comment on "On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens"

In the mBMSC assay, the data were more consistent between adipogenesis and gene induction, but they disagree qualitatively and quantitatively with the 3T3-L1 findings. [...]it is not clear how one could definitively compare the results from the Janesick et al. study to the ToxCast™ and Tox21 results...

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Veröffentlicht in:	Environmental health perspectives 2017-01, Vol.125 (1), p.A8-A11
Hauptverfasser:	Houck, Keith A, Judson, Richard S, Knudsen, Thomas B, Martin, Matthew T, Richard, Ann M, Crofton, Kevin M, Simeonov, Anton, Paules, Richard S, Bucher, John R, Thomas, Russell S
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological activity Biosynthesis Chemicals Correspondence Cytochrome Environmental Pollutants Humans Identification methods Kinases Ligands Pharmaceutical industry Phosphatase Studies Toxicology
Online-Zugang:	Volltext
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