Aurora-A promotes the establishment of spindle assembly checkpoint by priming the Haspin-Aurora-B feedback loop in late G2 phase

Aurora-A kinase functions mainly in centrosome maturation, separation and spindle formation. It has also been found to be amplified or overexpressed in a range of solid tumors, which is linked with tumor progression and poor prognosis. Importantly, Aurora-A inhibitors are being studied in a number o...

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Veröffentlicht in:	Cell discovery 2017-01, Vol.3 (1), p.16049-16049, Article 16049
Hauptverfasser:	Yu, Fazhi, Jiang, Ya, Lu, Lucy, Cao, Mimi, Qiao, Yulong, Liu, Xing, Liu, Dan, Van Dyke, Terry, Wang, Fangwei, Yao, Xuebiao, Guo, Jing, Yang, Zhenye
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/395 631/80/641/1655 Biomedical and Life Sciences Cell Biology Cell Culture Cell Cycle Analysis Cell Physiology Life Sciences Stem Cells
Online-Zugang:	Volltext
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