Long Non-Coding RNA: Potential Diagnostic and Therapeutic Biomarker for Major Depressive Disorder

BACKGROUND The criteria for diagnosing depression are based on behavioral observation and self-reporting of symptoms by the patients or guardians without any biological validation of the disease. This study aimed to identify long non-coding RNAs (lncRNAs) in peripheral blood mononuclear cells (PBMCs...

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Veröffentlicht in:	Medical science monitor 2016-12, Vol.22, p.5240-5248
Hauptverfasser:	Cui, Xuelian, Sun, Xinyang, Niu, Wei, Kong, Lingming, He, Mingjun, Zhong, Aifang, Chen, Shengdong, Jiang, Kunhong, Zhang, Liyi, Cheng, Zaohuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antidepressive Agents - therapeutic use Biomarkers - metabolism Case-Control Studies Clinical Research Depressive Disorder, Major - diagnosis Depressive Disorder, Major - drug therapy Depressive Disorder, Major - genetics Depressive Disorder, Major - therapy Female Gene Expression Profiling Gene Expression Regulation Gene Ontology Humans Male Oligonucleotide Array Sequence Analysis Real-Time Polymerase Chain Reaction Reproducibility of Results RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism ROC Curve
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