Phenolic Composition and Antioxidant and Antiproliferative Activities of the Extracts of Twelve Common Bean (Phaseolus vulgaris L.) Endemic Ecotypes of Southern Italy before and after Cooking
Beans are important dietary components with versatile health benefits. We analysed the extracts of twelve ecotypes of Phaseolus vulgaris in order to determine their phenolic profiles, antioxidant activity, and the in vitro antiproliferative activity. Ultra-performance liquid chromatography with diod...
Gespeichert in:
| Veröffentlicht in: | Oxidative medicine and cellular longevity 2016-01, Vol.2016 (2016), p.1-12 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 12 |
|---|---|
| container_issue | 2016 |
| container_start_page | 1 |
| container_title | Oxidative medicine and cellular longevity |
| container_volume | 2016 |
| creator | Fratianni, Florinda Maione, Mena Zaccardelli, Massimo Spigno, Patrizia Riccardi, Riccardo Nazzaro, Filomena d’Acierno, Antonio Ombra, Maria Neve Pane, Catello |
| description | Beans are important dietary components with versatile health benefits. We analysed the extracts of twelve ecotypes of Phaseolus vulgaris in order to determine their phenolic profiles, antioxidant activity, and the in vitro antiproliferative activity. Ultra-performance liquid chromatography with diode array detector (UPLC-DAD) admitted us to detect and quantify some known polyphenols, such as gallic acid, chlorogenic acid, epicatechin, myricetin, formononetin, caffeic acid, and kaempferol. The antioxidant activity (AA) ranged from 1.568 ± 0.041 to 66.572 ± 3.197 mg necessary to inhibit the activity of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical by 50% (EC50). The extracts, except those obtained from the nonpigmented samples, were capable of inhibiting the proliferation of the human epithelial colorectal adenocarcinoma (Caco-2) cells, human breast cancer cells MCF-7, and A549 NSCLC cell line. Cultivars differed in composition and concentration of polyphenols including anthocyanins; cooking affected the antioxidant activity only marginally. Qualitative and quantitative differences in phenolic composition between the groups of beans influenced the biological activities; on the other hand, we did not find significant differences on the biological activities within the same variety, before and after cooking. |
| doi_str_mv | 10.1155/2016/1398298 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5220516</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A555850373</galeid><sourcerecordid>A555850373</sourcerecordid><originalsourceid>FETCH-LOGICAL-c499t-47e5604f02f87a8d7d26b9c4eba95b4cf2c81b062d9f975e53133070f42635dc3</originalsourceid><addsrcrecordid>eNqNksFuEzEQhlcIREvhxhlZ4lIEaW2vvbu-IIUoQKVKVKKcLa93nLjs2sH2ps3T8Wo4TUiBEyfPyJ8_zVh_Ubwk-IwQzs8pJtU5KUVDRfOoOCaC0QkWgj0-1BgfFc9ivMG4KikjT4sj2hDMKWuOi59XS3C-txrN_LDy0SbrHVKuQ1OXyzvbKZcO_Spk1EBQya4BTXU-8gOIyBuUloDmdykone7761voM5S1QzZ-AOXQ6dVSRfD9GNF67Bcq2Iguz96guetgyCPMtU-b1U731Y_ZGBy6SKrfoBaMD3A_iDIJQvb679YtnhdPjOojvNifJ8W3j_Pr2efJ5ZdPF7Pp5UQzIdKE1cArzAympqlV09UdrVqhGbRK8JZpQ3VDWlzRThhRc-AlKUtcY8NoVfJOlyfF-513NbYDdBpc3rSXq2AHFTbSKyv_vnF2KRd-LTmlmJMqC073guB_jBCTHGzU0PfKgR-jJE1FeMMYZRl9_Q9648fg8nqZ4hWrKGPkgVqoHqR1xm__fiuVU855w3FZl5l6t6N08DEGMIeRCZbb_MhtfuQ-Pxl_9eeaB_h3YDLwdgcsrevUrf1PHWQGjHqgCSkrLMpf-Z7ZNA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1856462441</pqid></control><display><type>article</type><title>Phenolic Composition and Antioxidant and Antiproliferative Activities of the Extracts of Twelve Common Bean (Phaseolus vulgaris L.) Endemic Ecotypes of Southern Italy before and after Cooking</title><source>MEDLINE</source><source>PubMed Central Open Access</source><source>NCBI_PubMed Central（免费）</source><source>Wiley_OA刊</source><source>Free E-Journal (出版社公開部分のみ）</source><source>Alma/SFX Local Collection</source><creator>Fratianni, Florinda ; Maione, Mena ; Zaccardelli, Massimo ; Spigno, Patrizia ; Riccardi, Riccardo ; Nazzaro, Filomena ; d’Acierno, Antonio ; Ombra, Maria Neve ; Pane, Catello</creator><contributor>Peluso, Ilaria</contributor><creatorcontrib>Fratianni, Florinda ; Maione, Mena ; Zaccardelli, Massimo ; Spigno, Patrizia ; Riccardi, Riccardo ; Nazzaro, Filomena ; d’Acierno, Antonio ; Ombra, Maria Neve ; Pane, Catello ; Peluso, Ilaria</creatorcontrib><description>Beans are important dietary components with versatile health benefits. We analysed the extracts of twelve ecotypes of Phaseolus vulgaris in order to determine their phenolic profiles, antioxidant activity, and the in vitro antiproliferative activity. Ultra-performance liquid chromatography with diode array detector (UPLC-DAD) admitted us to detect and quantify some known polyphenols, such as gallic acid, chlorogenic acid, epicatechin, myricetin, formononetin, caffeic acid, and kaempferol. The antioxidant activity (AA) ranged from 1.568 ± 0.041 to 66.572 ± 3.197 mg necessary to inhibit the activity of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical by 50% (EC50). The extracts, except those obtained from the nonpigmented samples, were capable of inhibiting the proliferation of the human epithelial colorectal adenocarcinoma (Caco-2) cells, human breast cancer cells MCF-7, and A549 NSCLC cell line. Cultivars differed in composition and concentration of polyphenols including anthocyanins; cooking affected the antioxidant activity only marginally. Qualitative and quantitative differences in phenolic composition between the groups of beans influenced the biological activities; on the other hand, we did not find significant differences on the biological activities within the same variety, before and after cooking.</description><identifier>ISSN: 1942-0900</identifier><identifier>EISSN: 1942-0994</identifier><identifier>DOI: 10.1155/2016/1398298</identifier><identifier>PMID: 28105248</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>A549 Cells ; Anthocyanins - analysis ; Antioxidants ; Antioxidants - chemistry ; Antioxidants - pharmacology ; Beans ; Caco-2 Cells ; Cell Proliferation - drug effects ; Chemical properties ; Chromatography, High Pressure Liquid ; Common beans ; Cooking ; Cultivars ; Diabetes ; Dietary minerals ; Ecotype ; Flavonoids ; Flavonoids - analysis ; Functional foods & nutraceuticals ; Genetic aspects ; Humans ; Intraspecific genetic variation ; Italy ; Legumes ; Liquid chromatography ; MCF-7 Cells ; Nutrition research ; Phaseolus - chemistry ; Phaseolus - metabolism ; Plant Extracts - chemistry ; Plant Extracts - pharmacology ; Polyphenols ; Polyphenols - analysis ; Polyphenols - pharmacology ; Principal Component Analysis ; Principal components analysis</subject><ispartof>Oxidative medicine and cellular longevity, 2016-01, Vol.2016 (2016), p.1-12</ispartof><rights>Copyright © 2016 Maria Neve Ombra et al.</rights><rights>COPYRIGHT 2017 John Wiley & Sons, Inc.</rights><rights>Copyright © 2016 Maria Neve Ombra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2016 Maria Neve Ombra et al. 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c499t-47e5604f02f87a8d7d26b9c4eba95b4cf2c81b062d9f975e53133070f42635dc3</citedby><cites>FETCH-LOGICAL-c499t-47e5604f02f87a8d7d26b9c4eba95b4cf2c81b062d9f975e53133070f42635dc3</cites><orcidid>0000-0002-5759-7499</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220516/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220516/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,886,27926,27927,53793,53795</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28105248$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Peluso, Ilaria</contributor><creatorcontrib>Fratianni, Florinda</creatorcontrib><creatorcontrib>Maione, Mena</creatorcontrib><creatorcontrib>Zaccardelli, Massimo</creatorcontrib><creatorcontrib>Spigno, Patrizia</creatorcontrib><creatorcontrib>Riccardi, Riccardo</creatorcontrib><creatorcontrib>Nazzaro, Filomena</creatorcontrib><creatorcontrib>d’Acierno, Antonio</creatorcontrib><creatorcontrib>Ombra, Maria Neve</creatorcontrib><creatorcontrib>Pane, Catello</creatorcontrib><title>Phenolic Composition and Antioxidant and Antiproliferative Activities of the Extracts of Twelve Common Bean (Phaseolus vulgaris L.) Endemic Ecotypes of Southern Italy before and after Cooking</title><title>Oxidative medicine and cellular longevity</title><addtitle>Oxid Med Cell Longev</addtitle><description>Beans are important dietary components with versatile health benefits. We analysed the extracts of twelve ecotypes of Phaseolus vulgaris in order to determine their phenolic profiles, antioxidant activity, and the in vitro antiproliferative activity. Ultra-performance liquid chromatography with diode array detector (UPLC-DAD) admitted us to detect and quantify some known polyphenols, such as gallic acid, chlorogenic acid, epicatechin, myricetin, formononetin, caffeic acid, and kaempferol. The antioxidant activity (AA) ranged from 1.568 ± 0.041 to 66.572 ± 3.197 mg necessary to inhibit the activity of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical by 50% (EC50). The extracts, except those obtained from the nonpigmented samples, were capable of inhibiting the proliferation of the human epithelial colorectal adenocarcinoma (Caco-2) cells, human breast cancer cells MCF-7, and A549 NSCLC cell line. Cultivars differed in composition and concentration of polyphenols including anthocyanins; cooking affected the antioxidant activity only marginally. Qualitative and quantitative differences in phenolic composition between the groups of beans influenced the biological activities; on the other hand, we did not find significant differences on the biological activities within the same variety, before and after cooking.</description><subject>A549 Cells</subject><subject>Anthocyanins - analysis</subject><subject>Antioxidants</subject><subject>Antioxidants - chemistry</subject><subject>Antioxidants - pharmacology</subject><subject>Beans</subject><subject>Caco-2 Cells</subject><subject>Cell Proliferation - drug effects</subject><subject>Chemical properties</subject><subject>Chromatography, High Pressure Liquid</subject><subject>Common beans</subject><subject>Cooking</subject><subject>Cultivars</subject><subject>Diabetes</subject><subject>Dietary minerals</subject><subject>Ecotype</subject><subject>Flavonoids</subject><subject>Flavonoids - analysis</subject><subject>Functional foods & nutraceuticals</subject><subject>Genetic aspects</subject><subject>Humans</subject><subject>Intraspecific genetic variation</subject><subject>Italy</subject><subject>Legumes</subject><subject>Liquid chromatography</subject><subject>MCF-7 Cells</subject><subject>Nutrition research</subject><subject>Phaseolus - chemistry</subject><subject>Phaseolus - metabolism</subject><subject>Plant Extracts - chemistry</subject><subject>Plant Extracts - pharmacology</subject><subject>Polyphenols</subject><subject>Polyphenols - analysis</subject><subject>Polyphenols - pharmacology</subject><subject>Principal Component Analysis</subject><subject>Principal components analysis</subject><issn>1942-0900</issn><issn>1942-0994</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNksFuEzEQhlcIREvhxhlZ4lIEaW2vvbu-IIUoQKVKVKKcLa93nLjs2sH2ps3T8Wo4TUiBEyfPyJ8_zVh_Ubwk-IwQzs8pJtU5KUVDRfOoOCaC0QkWgj0-1BgfFc9ivMG4KikjT4sj2hDMKWuOi59XS3C-txrN_LDy0SbrHVKuQ1OXyzvbKZcO_Spk1EBQya4BTXU-8gOIyBuUloDmdykone7761voM5S1QzZ-AOXQ6dVSRfD9GNF67Bcq2Iguz96guetgyCPMtU-b1U731Y_ZGBy6SKrfoBaMD3A_iDIJQvb679YtnhdPjOojvNifJ8W3j_Pr2efJ5ZdPF7Pp5UQzIdKE1cArzAympqlV09UdrVqhGbRK8JZpQ3VDWlzRThhRc-AlKUtcY8NoVfJOlyfF-513NbYDdBpc3rSXq2AHFTbSKyv_vnF2KRd-LTmlmJMqC073guB_jBCTHGzU0PfKgR-jJE1FeMMYZRl9_Q9648fg8nqZ4hWrKGPkgVqoHqR1xm__fiuVU855w3FZl5l6t6N08DEGMIeRCZbb_MhtfuQ-Pxl_9eeaB_h3YDLwdgcsrevUrf1PHWQGjHqgCSkrLMpf-Z7ZNA</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>Fratianni, Florinda</creator><creator>Maione, Mena</creator><creator>Zaccardelli, Massimo</creator><creator>Spigno, Patrizia</creator><creator>Riccardi, Riccardo</creator><creator>Nazzaro, Filomena</creator><creator>d’Acierno, Antonio</creator><creator>Ombra, Maria Neve</creator><creator>Pane, Catello</creator><general>Hindawi Publishing Corporation</general><general>John Wiley & Sons, Inc</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-5759-7499</orcidid></search><sort><creationdate>20160101</creationdate><title>Phenolic Composition and Antioxidant and Antiproliferative Activities of the Extracts of Twelve Common Bean (Phaseolus vulgaris L.) Endemic Ecotypes of Southern Italy before and after Cooking</title><author>Fratianni, Florinda ; Maione, Mena ; Zaccardelli, Massimo ; Spigno, Patrizia ; Riccardi, Riccardo ; Nazzaro, Filomena ; d’Acierno, Antonio ; Ombra, Maria Neve ; Pane, Catello</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c499t-47e5604f02f87a8d7d26b9c4eba95b4cf2c81b062d9f975e53133070f42635dc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>A549 Cells</topic><topic>Anthocyanins - analysis</topic><topic>Antioxidants</topic><topic>Antioxidants - chemistry</topic><topic>Antioxidants - pharmacology</topic><topic>Beans</topic><topic>Caco-2 Cells</topic><topic>Cell Proliferation - drug effects</topic><topic>Chemical properties</topic><topic>Chromatography, High Pressure Liquid</topic><topic>Common beans</topic><topic>Cooking</topic><topic>Cultivars</topic><topic>Diabetes</topic><topic>Dietary minerals</topic><topic>Ecotype</topic><topic>Flavonoids</topic><topic>Flavonoids - analysis</topic><topic>Functional foods & nutraceuticals</topic><topic>Genetic aspects</topic><topic>Humans</topic><topic>Intraspecific genetic variation</topic><topic>Italy</topic><topic>Legumes</topic><topic>Liquid chromatography</topic><topic>MCF-7 Cells</topic><topic>Nutrition research</topic><topic>Phaseolus - chemistry</topic><topic>Phaseolus - metabolism</topic><topic>Plant Extracts - chemistry</topic><topic>Plant Extracts - pharmacology</topic><topic>Polyphenols</topic><topic>Polyphenols - analysis</topic><topic>Polyphenols - pharmacology</topic><topic>Principal Component Analysis</topic><topic>Principal components analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fratianni, Florinda</creatorcontrib><creatorcontrib>Maione, Mena</creatorcontrib><creatorcontrib>Zaccardelli, Massimo</creatorcontrib><creatorcontrib>Spigno, Patrizia</creatorcontrib><creatorcontrib>Riccardi, Riccardo</creatorcontrib><creatorcontrib>Nazzaro, Filomena</creatorcontrib><creatorcontrib>d’Acierno, Antonio</creatorcontrib><creatorcontrib>Ombra, Maria Neve</creatorcontrib><creatorcontrib>Pane, Catello</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest_Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Oxidative medicine and cellular longevity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fratianni, Florinda</au><au>Maione, Mena</au><au>Zaccardelli, Massimo</au><au>Spigno, Patrizia</au><au>Riccardi, Riccardo</au><au>Nazzaro, Filomena</au><au>d’Acierno, Antonio</au><au>Ombra, Maria Neve</au><au>Pane, Catello</au><au>Peluso, Ilaria</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phenolic Composition and Antioxidant and Antiproliferative Activities of the Extracts of Twelve Common Bean (Phaseolus vulgaris L.) Endemic Ecotypes of Southern Italy before and after Cooking</atitle><jtitle>Oxidative medicine and cellular longevity</jtitle><addtitle>Oxid Med Cell Longev</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>2016</volume><issue>2016</issue><spage>1</spage><epage>12</epage><pages>1-12</pages><issn>1942-0900</issn><eissn>1942-0994</eissn><abstract>Beans are important dietary components with versatile health benefits. We analysed the extracts of twelve ecotypes of Phaseolus vulgaris in order to determine their phenolic profiles, antioxidant activity, and the in vitro antiproliferative activity. Ultra-performance liquid chromatography with diode array detector (UPLC-DAD) admitted us to detect and quantify some known polyphenols, such as gallic acid, chlorogenic acid, epicatechin, myricetin, formononetin, caffeic acid, and kaempferol. The antioxidant activity (AA) ranged from 1.568 ± 0.041 to 66.572 ± 3.197 mg necessary to inhibit the activity of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical by 50% (EC50). The extracts, except those obtained from the nonpigmented samples, were capable of inhibiting the proliferation of the human epithelial colorectal adenocarcinoma (Caco-2) cells, human breast cancer cells MCF-7, and A549 NSCLC cell line. Cultivars differed in composition and concentration of polyphenols including anthocyanins; cooking affected the antioxidant activity only marginally. Qualitative and quantitative differences in phenolic composition between the groups of beans influenced the biological activities; on the other hand, we did not find significant differences on the biological activities within the same variety, before and after cooking.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>28105248</pmid><doi>10.1155/2016/1398298</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-5759-7499</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1942-0900 |
| ispartof | Oxidative medicine and cellular longevity, 2016-01, Vol.2016 (2016), p.1-12 |
| issn | 1942-0900 1942-0994 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5220516 |
| source | MEDLINE; PubMed Central Open Access; NCBI_PubMed Central（免费）; Wiley_OA刊; Free E-Journal (出版社公開部分のみ）; Alma/SFX Local Collection |
| subjects | A549 Cells Anthocyanins - analysis Antioxidants Antioxidants - chemistry Antioxidants - pharmacology Beans Caco-2 Cells Cell Proliferation - drug effects Chemical properties Chromatography, High Pressure Liquid Common beans Cooking Cultivars Diabetes Dietary minerals Ecotype Flavonoids Flavonoids - analysis Functional foods & nutraceuticals Genetic aspects Humans Intraspecific genetic variation Italy Legumes Liquid chromatography MCF-7 Cells Nutrition research Phaseolus - chemistry Phaseolus - metabolism Plant Extracts - chemistry Plant Extracts - pharmacology Polyphenols Polyphenols - analysis Polyphenols - pharmacology Principal Component Analysis Principal components analysis |
| title | Phenolic Composition and Antioxidant and Antiproliferative Activities of the Extracts of Twelve Common Bean (Phaseolus vulgaris L.) Endemic Ecotypes of Southern Italy before and after Cooking |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-17T15%3A08%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Phenolic%20Composition%20and%20Antioxidant%20and%20Antiproliferative%20Activities%20of%20the%20Extracts%20of%20Twelve%20Common%20Bean%20(Phaseolus%20vulgaris%20L.)%20Endemic%20Ecotypes%20of%20Southern%20Italy%20before%20and%20after%20Cooking&rft.jtitle=Oxidative%20medicine%20and%20cellular%20longevity&rft.au=Fratianni,%20Florinda&rft.date=2016-01-01&rft.volume=2016&rft.issue=2016&rft.spage=1&rft.epage=12&rft.pages=1-12&rft.issn=1942-0900&rft.eissn=1942-0994&rft_id=info:doi/10.1155/2016/1398298&rft_dat=%3Cgale_pubme%3EA555850373%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1856462441&rft_id=info:pmid/28105248&rft_galeid=A555850373&rfr_iscdi=true |