Arabidopsis nonsymbiotic hemoglobin AHb1 modulates nitric oxide bioactivity
Nitric oxide (NO) is a widespread signaling molecule, and numerous targets of its action exist in plants. Whereas the activity of NO in erythrocytes, microorganisms, and invertebrates has been shown to be regulated by several hemoglobins, the function of plant hemoglobins in NO detoxification has no...
Gespeichert in:
| Veröffentlicht in: | The Plant cell 2004-10, Vol.16 (10), p.2785-2794 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2794 |
|---|---|
| container_issue | 10 |
| container_start_page | 2785 |
| container_title | The Plant cell |
| container_volume | 16 |
| creator | Perazzolli, M Dominici, P Romero-Puetas, M.C Zago, E Zeier, J Sonoda, M Lamb, C Delledonne, M |
| description | Nitric oxide (NO) is a widespread signaling molecule, and numerous targets of its action exist in plants. Whereas the activity of NO in erythrocytes, microorganisms, and invertebrates has been shown to be regulated by several hemoglobins, the function of plant hemoglobins in NO detoxification has not yet been elucidated. Here, we show that Arabidopsis thaliana nonsymbiotic hemoglobin AHb1 scavenges NO through production of S-nitrosohemoglobin and reduces NO emission under hypoxic stress, indicating its role in NO detoxification. However, AHb1 does not affect NO-mediated hypersensitive cell death in response to avirulent Pseudomonas syringae, suggesting that it is not involved in the removal of NO bursts originated from acute responses when NO mediates crucial defense signaling functions. |
| doi_str_mv | 10.1105/tpc.104.025379 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_520971</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>3872264</jstor_id><sourcerecordid>3872264</sourcerecordid><originalsourceid>FETCH-LOGICAL-c524t-9b443f891c68782434dbdfb930dc3b56d6e05a2a347ce46c5920ba8a88a3af33</originalsourceid><addsrcrecordid>eNqF0btvFDEQB2ALgUgItFQIVhR0e_j9KFKcIvIQkSgIEp1le70Xn3bXh-2NuP8-RnsKCQ2VR5pvrLF_ALxFcIUQZJ_Lzq0QpCuIGRHqGThGjOAWK_nzea0hhS3lDB2BVzlvIYRIIPUSHFXEhUD8GHxdJ2NDF3c55GaKU96PNsQSXHPrx7gZog1Ts760qBljNw-m-MpCSRXE36HzTdXGlXAXyv41eNGbIfs3h_ME3Jx_uTm7bK-_XVydra9bxzAtrbKUkl4q5LgUElNCO9v1VhHYOWIZ77iHzGBDqHCecscUhtZII6UhpifkBJwu1-5mO_rO-akkM-hdCqNJex1N0E87U7jVm3inGYZKoDr_6TCf4q_Z56LHkJ0fBjP5OGfNuaKCKv5fiJTEmAhR4cd_4DbOaap_oDGSQmAGZUWrBbkUc06-f9gYQf0nS12zrDXVS5Z14P3jd_7lh_AqeLeAbS4xPfSJFBhzWtsflnZvojabFLL-8R1DRCBUrG4tyT2rSa5e</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>218772508</pqid></control><display><type>article</type><title>Arabidopsis nonsymbiotic hemoglobin AHb1 modulates nitric oxide bioactivity</title><source>MEDLINE</source><source>JSTOR Archive Collection A-Z Listing</source><source>Oxford University Press Journals All Titles (1996-Current)</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Perazzolli, M ; Dominici, P ; Romero-Puetas, M.C ; Zago, E ; Zeier, J ; Sonoda, M ; Lamb, C ; Delledonne, M</creator><creatorcontrib>Perazzolli, M ; Dominici, P ; Romero-Puetas, M.C ; Zago, E ; Zeier, J ; Sonoda, M ; Lamb, C ; Delledonne, M</creatorcontrib><description>Nitric oxide (NO) is a widespread signaling molecule, and numerous targets of its action exist in plants. Whereas the activity of NO in erythrocytes, microorganisms, and invertebrates has been shown to be regulated by several hemoglobins, the function of plant hemoglobins in NO detoxification has not yet been elucidated. Here, we show that Arabidopsis thaliana nonsymbiotic hemoglobin AHb1 scavenges NO through production of S-nitrosohemoglobin and reduces NO emission under hypoxic stress, indicating its role in NO detoxification. However, AHb1 does not affect NO-mediated hypersensitive cell death in response to avirulent Pseudomonas syringae, suggesting that it is not involved in the removal of NO bursts originated from acute responses when NO mediates crucial defense signaling functions.</description><identifier>ISSN: 1040-4651</identifier><identifier>EISSN: 1532-298X</identifier><identifier>DOI: 10.1105/tpc.104.025379</identifier><identifier>PMID: 15367716</identifier><language>eng</language><publisher>England: American Society of Plant Biologists</publisher><subject>Antibodies ; Arabidopsis - physiology ; Arabidopsis Proteins - physiology ; Arabidopsis thaliana ; bacterial diseases of plants ; Base Sequence ; Detoxification ; disease resistance ; DNA Primers ; enzyme activity ; Gels ; Hemoglobins ; Hemoglobins - physiology ; hypersensitive response ; Hypoxia ; Immunoprecipitation ; Leaves ; metabolic detoxification ; Microorganisms ; Nitrates ; Nitric oxide ; Nitric Oxide - physiology ; nitric oxide dioxygenase ; Oxides ; Oxygen ; oxygenases ; Plant cells ; plant pathogenic bacteria ; plant proteins ; plant stress ; Plants ; Plants, Genetically Modified - physiology ; Pseudomonas syringae ; Recombinant Proteins - metabolism</subject><ispartof>The Plant cell, 2004-10, Vol.16 (10), p.2785-2794</ispartof><rights>Copyright 2004 American Society of Plant Biologists</rights><rights>Copyright American Society of Plant Physiologists Oct 2004</rights><rights>Copyright © 2004, American Society of Plant Biologists 2004</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c524t-9b443f891c68782434dbdfb930dc3b56d6e05a2a347ce46c5920ba8a88a3af33</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/3872264$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/3872264$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,780,784,803,885,27924,27925,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15367716$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Perazzolli, M</creatorcontrib><creatorcontrib>Dominici, P</creatorcontrib><creatorcontrib>Romero-Puetas, M.C</creatorcontrib><creatorcontrib>Zago, E</creatorcontrib><creatorcontrib>Zeier, J</creatorcontrib><creatorcontrib>Sonoda, M</creatorcontrib><creatorcontrib>Lamb, C</creatorcontrib><creatorcontrib>Delledonne, M</creatorcontrib><title>Arabidopsis nonsymbiotic hemoglobin AHb1 modulates nitric oxide bioactivity</title><title>The Plant cell</title><addtitle>Plant Cell</addtitle><description>Nitric oxide (NO) is a widespread signaling molecule, and numerous targets of its action exist in plants. Whereas the activity of NO in erythrocytes, microorganisms, and invertebrates has been shown to be regulated by several hemoglobins, the function of plant hemoglobins in NO detoxification has not yet been elucidated. Here, we show that Arabidopsis thaliana nonsymbiotic hemoglobin AHb1 scavenges NO through production of S-nitrosohemoglobin and reduces NO emission under hypoxic stress, indicating its role in NO detoxification. However, AHb1 does not affect NO-mediated hypersensitive cell death in response to avirulent Pseudomonas syringae, suggesting that it is not involved in the removal of NO bursts originated from acute responses when NO mediates crucial defense signaling functions.</description><subject>Antibodies</subject><subject>Arabidopsis - physiology</subject><subject>Arabidopsis Proteins - physiology</subject><subject>Arabidopsis thaliana</subject><subject>bacterial diseases of plants</subject><subject>Base Sequence</subject><subject>Detoxification</subject><subject>disease resistance</subject><subject>DNA Primers</subject><subject>enzyme activity</subject><subject>Gels</subject><subject>Hemoglobins</subject><subject>Hemoglobins - physiology</subject><subject>hypersensitive response</subject><subject>Hypoxia</subject><subject>Immunoprecipitation</subject><subject>Leaves</subject><subject>metabolic detoxification</subject><subject>Microorganisms</subject><subject>Nitrates</subject><subject>Nitric oxide</subject><subject>Nitric Oxide - physiology</subject><subject>nitric oxide dioxygenase</subject><subject>Oxides</subject><subject>Oxygen</subject><subject>oxygenases</subject><subject>Plant cells</subject><subject>plant pathogenic bacteria</subject><subject>plant proteins</subject><subject>plant stress</subject><subject>Plants</subject><subject>Plants, Genetically Modified - physiology</subject><subject>Pseudomonas syringae</subject><subject>Recombinant Proteins - metabolism</subject><issn>1040-4651</issn><issn>1532-298X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqF0btvFDEQB2ALgUgItFQIVhR0e_j9KFKcIvIQkSgIEp1le70Xn3bXh-2NuP8-RnsKCQ2VR5pvrLF_ALxFcIUQZJ_Lzq0QpCuIGRHqGThGjOAWK_nzea0hhS3lDB2BVzlvIYRIIPUSHFXEhUD8GHxdJ2NDF3c55GaKU96PNsQSXHPrx7gZog1Ts760qBljNw-m-MpCSRXE36HzTdXGlXAXyv41eNGbIfs3h_ME3Jx_uTm7bK-_XVydra9bxzAtrbKUkl4q5LgUElNCO9v1VhHYOWIZ77iHzGBDqHCecscUhtZII6UhpifkBJwu1-5mO_rO-akkM-hdCqNJex1N0E87U7jVm3inGYZKoDr_6TCf4q_Z56LHkJ0fBjP5OGfNuaKCKv5fiJTEmAhR4cd_4DbOaap_oDGSQmAGZUWrBbkUc06-f9gYQf0nS12zrDXVS5Z14P3jd_7lh_AqeLeAbS4xPfSJFBhzWtsflnZvojabFLL-8R1DRCBUrG4tyT2rSa5e</recordid><startdate>20041001</startdate><enddate>20041001</enddate><creator>Perazzolli, M</creator><creator>Dominici, P</creator><creator>Romero-Puetas, M.C</creator><creator>Zago, E</creator><creator>Zeier, J</creator><creator>Sonoda, M</creator><creator>Lamb, C</creator><creator>Delledonne, M</creator><general>American Society of Plant Biologists</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>4T-</scope><scope>7QO</scope><scope>7TM</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>RC3</scope><scope>S0X</scope><scope>7QL</scope><scope>7T7</scope><scope>C1K</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20041001</creationdate><title>Arabidopsis nonsymbiotic hemoglobin AHb1 modulates nitric oxide bioactivity</title><author>Perazzolli, M ; Dominici, P ; Romero-Puetas, M.C ; Zago, E ; Zeier, J ; Sonoda, M ; Lamb, C ; Delledonne, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c524t-9b443f891c68782434dbdfb930dc3b56d6e05a2a347ce46c5920ba8a88a3af33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Antibodies</topic><topic>Arabidopsis - physiology</topic><topic>Arabidopsis Proteins - physiology</topic><topic>Arabidopsis thaliana</topic><topic>bacterial diseases of plants</topic><topic>Base Sequence</topic><topic>Detoxification</topic><topic>disease resistance</topic><topic>DNA Primers</topic><topic>enzyme activity</topic><topic>Gels</topic><topic>Hemoglobins</topic><topic>Hemoglobins - physiology</topic><topic>hypersensitive response</topic><topic>Hypoxia</topic><topic>Immunoprecipitation</topic><topic>Leaves</topic><topic>metabolic detoxification</topic><topic>Microorganisms</topic><topic>Nitrates</topic><topic>Nitric oxide</topic><topic>Nitric Oxide - physiology</topic><topic>nitric oxide dioxygenase</topic><topic>Oxides</topic><topic>Oxygen</topic><topic>oxygenases</topic><topic>Plant cells</topic><topic>plant pathogenic bacteria</topic><topic>plant proteins</topic><topic>plant stress</topic><topic>Plants</topic><topic>Plants, Genetically Modified - physiology</topic><topic>Pseudomonas syringae</topic><topic>Recombinant Proteins - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Perazzolli, M</creatorcontrib><creatorcontrib>Dominici, P</creatorcontrib><creatorcontrib>Romero-Puetas, M.C</creatorcontrib><creatorcontrib>Zago, E</creatorcontrib><creatorcontrib>Zeier, J</creatorcontrib><creatorcontrib>Sonoda, M</creatorcontrib><creatorcontrib>Lamb, C</creatorcontrib><creatorcontrib>Delledonne, M</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>Biotechnology Research Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><collection>SIRS Editorial</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Plant cell</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Perazzolli, M</au><au>Dominici, P</au><au>Romero-Puetas, M.C</au><au>Zago, E</au><au>Zeier, J</au><au>Sonoda, M</au><au>Lamb, C</au><au>Delledonne, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Arabidopsis nonsymbiotic hemoglobin AHb1 modulates nitric oxide bioactivity</atitle><jtitle>The Plant cell</jtitle><addtitle>Plant Cell</addtitle><date>2004-10-01</date><risdate>2004</risdate><volume>16</volume><issue>10</issue><spage>2785</spage><epage>2794</epage><pages>2785-2794</pages><issn>1040-4651</issn><eissn>1532-298X</eissn><abstract>Nitric oxide (NO) is a widespread signaling molecule, and numerous targets of its action exist in plants. Whereas the activity of NO in erythrocytes, microorganisms, and invertebrates has been shown to be regulated by several hemoglobins, the function of plant hemoglobins in NO detoxification has not yet been elucidated. Here, we show that Arabidopsis thaliana nonsymbiotic hemoglobin AHb1 scavenges NO through production of S-nitrosohemoglobin and reduces NO emission under hypoxic stress, indicating its role in NO detoxification. However, AHb1 does not affect NO-mediated hypersensitive cell death in response to avirulent Pseudomonas syringae, suggesting that it is not involved in the removal of NO bursts originated from acute responses when NO mediates crucial defense signaling functions.</abstract><cop>England</cop><pub>American Society of Plant Biologists</pub><pmid>15367716</pmid><doi>10.1105/tpc.104.025379</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1040-4651 |
| ispartof | The Plant cell, 2004-10, Vol.16 (10), p.2785-2794 |
| issn | 1040-4651 1532-298X |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_520971 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals |
| subjects | Antibodies Arabidopsis - physiology Arabidopsis Proteins - physiology Arabidopsis thaliana bacterial diseases of plants Base Sequence Detoxification disease resistance DNA Primers enzyme activity Gels Hemoglobins Hemoglobins - physiology hypersensitive response Hypoxia Immunoprecipitation Leaves metabolic detoxification Microorganisms Nitrates Nitric oxide Nitric Oxide - physiology nitric oxide dioxygenase Oxides Oxygen oxygenases Plant cells plant pathogenic bacteria plant proteins plant stress Plants Plants, Genetically Modified - physiology Pseudomonas syringae Recombinant Proteins - metabolism |
| title | Arabidopsis nonsymbiotic hemoglobin AHb1 modulates nitric oxide bioactivity |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T11%3A52%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Arabidopsis%20nonsymbiotic%20hemoglobin%20AHb1%20modulates%20nitric%20oxide%20bioactivity&rft.jtitle=The%20Plant%20cell&rft.au=Perazzolli,%20M&rft.date=2004-10-01&rft.volume=16&rft.issue=10&rft.spage=2785&rft.epage=2794&rft.pages=2785-2794&rft.issn=1040-4651&rft.eissn=1532-298X&rft_id=info:doi/10.1105/tpc.104.025379&rft_dat=%3Cjstor_pubme%3E3872264%3C/jstor_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=218772508&rft_id=info:pmid/15367716&rft_jstor_id=3872264&rfr_iscdi=true |