Genetically decreased vitamin D and risk of Alzheimer disease

OBJECTIVE:To test whether genetically decreased vitamin D levels are associated with Alzheimer disease (AD) using mendelian randomization (MR), a method that minimizes bias due to confounding or reverse causation. METHODS:We selected single nucleotide polymorphisms (SNPs) that are strongly associate...

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Veröffentlicht in:	Neurology 2016-12, Vol.87 (24), p.2567-2574
Hauptverfasser:	Mokry, Lauren E, Ross, Stephanie, Morris, John A, Manousaki, Despoina, Forgetta, Vincenzo, Richards, J Brent
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - diagnosis Alzheimer Disease - genetics Canada Dietary Supplements Humans Mendelian Randomization Analysis - methods Osteoporosis - genetics Phenotype Polymorphism, Single Nucleotide - genetics Risk Factors Vitamin D - blood
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