Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations
In recent years, nutraceuticals attracted a great amount of attention in the biomedical research due to their significant contribution as natural agents for prevention of various health issues. Ethanolic extracts from the ungerminated and germinated seeds of Lupinus albus L. and Lupinus angustifoliu...
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| Veröffentlicht in: | Evidence-based complementary and alternative medicine 2016-01, Vol.2016 (2016), p.1-8 |
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| creator | Mioc, Marius Cristina, Romeo Teodor Soica, Codruta Dehelean, Cristina Pinzaru, Iulia Coricovac, Dorina Cioca, Andreea Hogea, Elena Zupkó, István Alexa, Ersilia Danciu, Corina Andor, Bogdan Patrascu, Jenel Marian |
| description | In recent years, nutraceuticals attracted a great amount of attention in the biomedical research due to their significant contribution as natural agents for prevention of various health issues. Ethanolic extracts from the ungerminated and germinated seeds of Lupinus albus L. and Lupinus angustifolius L. were analyzed for the content in isoflavones (genistein) and cinnamic acid derivatives. Additionally, the extracts were evaluated for antimicrobial, antiproliferative, and anti-inflammatory properties, using in vitro and in vivo tests. Germination proved to be a method of choice in increasing the amount of genistein and cinnamic acid derivatives in both Lupinus albus L. and Lupinus angustifolius L. seeds. Biological evaluation of all vegetal extracts revealed a weak therapeutic potential for both ungerminated and germinated seeds. |
| doi_str_mv | 10.1155/2016/7638542 |
| format | Article |
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Ethanolic extracts from the ungerminated and germinated seeds of Lupinus albus L. and Lupinus angustifolius L. were analyzed for the content in isoflavones (genistein) and cinnamic acid derivatives. Additionally, the extracts were evaluated for antimicrobial, antiproliferative, and anti-inflammatory properties, using in vitro and in vivo tests. Germination proved to be a method of choice in increasing the amount of genistein and cinnamic acid derivatives in both Lupinus albus L. and Lupinus angustifolius L. seeds. Biological evaluation of all vegetal extracts revealed a weak therapeutic potential for both ungerminated and germinated seeds.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2016/7638542</identifier><identifier>PMID: 28090213</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Acids ; Amino acids ; Analysis ; Animals ; Edema ; Ethanol ; Functional foods & nutraceuticals ; Germination ; Health aspects ; Isoflavones ; Pharmacy ; Seeds ; Studies ; Veterinary medicine</subject><ispartof>Evidence-based complementary and alternative medicine, 2016-01, Vol.2016 (2016), p.1-8</ispartof><rights>Copyright © 2016 Bogdan Andor et al.</rights><rights>COPYRIGHT 2017 John Wiley & Sons, Inc.</rights><rights>Copyright © 2016 Bogdan Andor et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2016 Bogdan Andor et al. 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c499t-f68f6dfe74911b090c5d37cb7ec01184c8b5d929c57afba36959a8676a73a9453</citedby><cites>FETCH-LOGICAL-c499t-f68f6dfe74911b090c5d37cb7ec01184c8b5d929c57afba36959a8676a73a9453</cites><orcidid>0000-0003-2215-6666 ; 0000-0003-3243-5300 ; 0000-0003-2295-1926 ; 0000-0001-5999-1214</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206418/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206418/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28090213$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Ríos, José L.</contributor><creatorcontrib>Mioc, Marius</creatorcontrib><creatorcontrib>Cristina, Romeo Teodor</creatorcontrib><creatorcontrib>Soica, Codruta</creatorcontrib><creatorcontrib>Dehelean, Cristina</creatorcontrib><creatorcontrib>Pinzaru, Iulia</creatorcontrib><creatorcontrib>Coricovac, Dorina</creatorcontrib><creatorcontrib>Cioca, Andreea</creatorcontrib><creatorcontrib>Hogea, Elena</creatorcontrib><creatorcontrib>Zupkó, István</creatorcontrib><creatorcontrib>Alexa, Ersilia</creatorcontrib><creatorcontrib>Danciu, Corina</creatorcontrib><creatorcontrib>Andor, Bogdan</creatorcontrib><creatorcontrib>Patrascu, Jenel Marian</creatorcontrib><title>Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations</title><title>Evidence-based complementary and alternative medicine</title><addtitle>Evid Based Complement Alternat Med</addtitle><description>In recent years, nutraceuticals attracted a great amount of attention in the biomedical research due to their significant contribution as natural agents for prevention of various health issues. 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L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations</atitle><jtitle>Evidence-based complementary and alternative medicine</jtitle><addtitle>Evid Based Complement Alternat Med</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>2016</volume><issue>2016</issue><spage>1</spage><epage>8</epage><pages>1-8</pages><issn>1741-427X</issn><eissn>1741-4288</eissn><abstract>In recent years, nutraceuticals attracted a great amount of attention in the biomedical research due to their significant contribution as natural agents for prevention of various health issues. Ethanolic extracts from the ungerminated and germinated seeds of Lupinus albus L. and Lupinus angustifolius L. were analyzed for the content in isoflavones (genistein) and cinnamic acid derivatives. Additionally, the extracts were evaluated for antimicrobial, antiproliferative, and anti-inflammatory properties, using in vitro and in vivo tests. Germination proved to be a method of choice in increasing the amount of genistein and cinnamic acid derivatives in both Lupinus albus L. and Lupinus angustifolius L. seeds. 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| fulltext | fulltext |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; Wiley Online Library Open Access; PubMed Central; Alma/SFX Local Collection |
| subjects | Acids Amino acids Analysis Animals Edema Ethanol Functional foods & nutraceuticals Germination Health aspects Isoflavones Pharmacy Seeds Studies Veterinary medicine |
| title | Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations |
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