Role of N -Methyl-D-Aspartate Receptors in Action-Based Predictive Coding Deficits in Schizophrenia

Abstract Background Recent theoretical models of schizophrenia posit that dysfunction of the neural mechanisms subserving predictive coding contributes to symptoms and cognitive deficits, and this dysfunction is further posited to result from N -methyl-D-aspartate glutamate receptor (NMDAR) hypofunc...

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Veröffentlicht in:	Biological psychiatry (1969) 2017-03, Vol.81 (6), p.514-524
Hauptverfasser:	Kort, Naomi S, Ford, Judith M, Roach, Brian J, Gunduz-Bruce, Handan, Krystal, John H, Jaeger, Judith, Reinhart, Robert M.G, Mathalon, Daniel H
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation Adult Cerebral Cortex - physiopathology Cross-Over Studies Electroencephalography Evoked Potentials Female Humans Ketamine Male N-methyl-D-aspartate glutamate receptor Predictive coding Psychiatry Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors Receptors, N-Methyl-D-Aspartate - physiology Schizophrenia Schizophrenia - physiopathology Schizophrenic Psychology Speech motor control Speech Perception - physiology
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