Randomized Trial of Thymectomy in Myasthenia Gravis

In patients with nonthymomatous myasthenia gravis, thymectomy plus prednisone was associated with better clinical outcomes than prednisone alone. Patients treated with thymectomy had fewer hospitalizations for exacerbations and required lower prednisone doses. The first reported use of thymectomy in...

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Veröffentlicht in:	The New England journal of medicine 2016-08, Vol.375 (6), p.511-522
Hauptverfasser:	Wolfe, Gil I, Kaminski, Henry J, Aban, Inmaculada B, Minisman, Greg, Kuo, Hui-Chien, Marx, Alexander, Ströbel, Philipp, Mazia, Claudio, Oger, Joel, Cea, J. Gabriel, Heckmann, Jeannine M, Evoli, Amelia, Nix, Wilfred, Ciafaloni, Emma, Antonini, Giovanni, Witoonpanich, Rawiphan, King, John O, Beydoun, Said R, Chalk, Colin H, Barboi, Alexandru C, Amato, Anthony A, Shaibani, Aziz I, Katirji, Bashar, Lecky, Bryan R.F, Buckley, Camilla, Vincent, Angela, Dias-Tosta, Elza, Yoshikawa, Hiroaki, Waddington-Cruz, Márcia, Pulley, Michael T, Rivner, Michael H, Kostera-Pruszczyk, Anna, Pascuzzi, Robert M, Jackson, Carlayne E, Garcia Ramos, Guillermo S, Verschuuren, Jan J.G.M, Massey, Janice M, Kissel, John T, Werneck, Lineu C, Benatar, Michael, Barohn, Richard J, Tandan, Rup, Mozaffar, Tahseen, Conwit, Robin, Odenkirchen, Joanne, Sonett, Joshua R, Jaretzki, Alfred, Newsom-Davis, John, Cutter, Gary R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Azathioprine Clinical trials Combined Modality Therapy Evidence-based medicine Female Glucocorticoids - administration & dosage Hospitalization Humans Immunosuppression Lymphatic system Male Middle Aged Myasthenia gravis Myasthenia Gravis - classification Myasthenia Gravis - drug therapy Myasthenia Gravis - surgery Neurological diseases Neuromuscular diseases Neuromuscular junctions Patients Prednisone Prednisone - administration & dosage Quality of life Severity of Illness Index Single-Blind Method Surgery Thymectomy Treatment Outcome Young Adult
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