Roux-En-Y Gastric Bypass Vs. Sleeve Gastrectomy: Balancing the Risks of Surgery with the Benefits of Weight Loss
Background The purpose of the study was to compare weight loss, metabolic parameters, and postoperative complications in patients undergoing Roux-en-Y gastric bypass (GB) and sleeve gastrectomy (SG). Methods We retrospectively studied 30-day postoperative complications as well as change in weight, b...
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| Veröffentlicht in: | Obesity surgery 2017-01, Vol.27 (1), p.154-161 |
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| creator | Lager, Corey J. Esfandiari, Nazanene H. Subauste, Angela R. Kraftson, Andrew T. Brown, Morton B. Cassidy, Ruth B. Nay, Catherine K. Lockwood, Amy L. Varban, Oliver A. Oral, Elif A. |
| description | Background
The purpose of the study was to compare weight loss, metabolic parameters, and postoperative complications in patients undergoing Roux-en-Y gastric bypass (GB) and sleeve gastrectomy (SG).
Methods
We retrospectively studied 30-day postoperative complications as well as change in weight, blood pressure, cholesterol, hemoglobin, hemoglobin A1C, and creatinine from baseline to 2, 6, 12, and 24 months postoperatively in 383 patients undergoing GB and 336 patients undergoing SG at the University of Michigan from January 2008 to November 2013. For a study population which typically has high attrition rates, there were excellent follow-up rates (706/719 at 2 months, 566/719 at 6 months, 519/719 at 12 months, and 382/719 at 24 months).
Results
Baseline characteristics were similar in both groups except for higher weight and BMI in the SG group. The GB group experienced greater total body weight loss at 6, 12, and 24 months (41.9 vs. 34.6 kg at 24 months,
p
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| doi_str_mv | 10.1007/s11695-016-2265-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5187368</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4287150481</sourcerecordid><originalsourceid>FETCH-LOGICAL-c470t-f98bf4b54e4fb2077854ef06eee20f69f2b76177c930dca3648654b9623092193</originalsourceid><addsrcrecordid>eNp1kV1rFDEUhoModq3-AG8k4I03qfmYSSZeCN1Sq7Ag9BOvQiY92U2dnVmTTHX_velOLVXwIiTwPuc95-RF6DWjB4xS9T4xJnVNKJOEc1kT_gTNmKINoRVvnqIZ1ZKSRnOxh16kdEMpZ5Lz52iPK1GVo2doczqMv8hxT77hE5tyDA7PtxubEr5MB_isA7iFSQGXh_X2A57bzvYu9EucV4BPQ_qe8ODx2RiXELf4Z8irnTKHHnzIO_EKwnKV8WJI6SV65m2X4NX9vY8uPh2fH30mi68nX44OF8RVimbiddP6qq0rqHzLqVJNeXoqAYBTL7XnrZJMKacFvXZWyKqRddVqyQXVnGmxjz5OvpuxXcO1gz5H25lNDGsbt2awwfyt9GFllsOtqVmjhGyKwbt7gzj8GCFlsw7JQVe2h2FMhjVcKiqkqAv69h_0ZhhjX9YrVM11mW1HsYlysfxDBP8wDKPmLk8z5WlKnuYuT8NLzZvHWzxU_AmwAHwCUpH6ksCj1v91_Q1bfKqW</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1852948635</pqid></control><display><type>article</type><title>Roux-En-Y Gastric Bypass Vs. Sleeve Gastrectomy: Balancing the Risks of Surgery with the Benefits of Weight Loss</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Lager, Corey J. ; Esfandiari, Nazanene H. ; Subauste, Angela R. ; Kraftson, Andrew T. ; Brown, Morton B. ; Cassidy, Ruth B. ; Nay, Catherine K. ; Lockwood, Amy L. ; Varban, Oliver A. ; Oral, Elif A.</creator><creatorcontrib>Lager, Corey J. ; Esfandiari, Nazanene H. ; Subauste, Angela R. ; Kraftson, Andrew T. ; Brown, Morton B. ; Cassidy, Ruth B. ; Nay, Catherine K. ; Lockwood, Amy L. ; Varban, Oliver A. ; Oral, Elif A.</creatorcontrib><description>Background
The purpose of the study was to compare weight loss, metabolic parameters, and postoperative complications in patients undergoing Roux-en-Y gastric bypass (GB) and sleeve gastrectomy (SG).
Methods
We retrospectively studied 30-day postoperative complications as well as change in weight, blood pressure, cholesterol, hemoglobin, hemoglobin A1C, and creatinine from baseline to 2, 6, 12, and 24 months postoperatively in 383 patients undergoing GB and 336 patients undergoing SG at the University of Michigan from January 2008 to November 2013. For a study population which typically has high attrition rates, there were excellent follow-up rates (706/719 at 2 months, 566/719 at 6 months, 519/719 at 12 months, and 382/719 at 24 months).
Results
Baseline characteristics were similar in both groups except for higher weight and BMI in the SG group. The GB group experienced greater total body weight loss at 6, 12, and 24 months (41.9 vs. 34.6 kg at 24 months,
p
< 0.0001). Excess weight loss was 69.7 and 51.7 % following GB and SG respectively at 24 months (
p
< 0.0001). BP improved significantly in both groups. Surgical complication rates were greater after GB (10.1 vs. 3.5 %,
p
= 0.0007) with no significant difference in life-threatening or potentially life-threatening complications.
Conclusions
Weight loss was greater following GB compared to SG at 2 years. The risk for surgical complications was greater following GB. Surgical intervention should be tailored to surgical risk, comorbidities, and desired weight loss.</description><identifier>ISSN: 0960-8923</identifier><identifier>EISSN: 1708-0428</identifier><identifier>DOI: 10.1007/s11695-016-2265-2</identifier><identifier>PMID: 27342739</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adult ; Comorbidity ; Female ; Gastrectomy - adverse effects ; Gastrectomy - methods ; Gastrectomy - statistics & numerical data ; Gastric Bypass - adverse effects ; Gastric Bypass - methods ; Gastric Bypass - statistics & numerical data ; Gastrointestinal surgery ; Humans ; Laparoscopy - adverse effects ; Male ; Medicine ; Medicine & Public Health ; Metabolism ; Middle Aged ; Obesity ; Obesity, Morbid - epidemiology ; Obesity, Morbid - surgery ; Original Contributions ; Postoperative Complications - epidemiology ; Postoperative Complications - etiology ; Retrospective Studies ; Risk Assessment ; Surgery ; Treatment Outcome ; Weight control ; Weight Loss - physiology</subject><ispartof>Obesity surgery, 2017-01, Vol.27 (1), p.154-161</ispartof><rights>The Author(s) 2016</rights><rights>Obesity Surgery is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-f98bf4b54e4fb2077854ef06eee20f69f2b76177c930dca3648654b9623092193</citedby><cites>FETCH-LOGICAL-c470t-f98bf4b54e4fb2077854ef06eee20f69f2b76177c930dca3648654b9623092193</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11695-016-2265-2$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11695-016-2265-2$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27342739$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lager, Corey J.</creatorcontrib><creatorcontrib>Esfandiari, Nazanene H.</creatorcontrib><creatorcontrib>Subauste, Angela R.</creatorcontrib><creatorcontrib>Kraftson, Andrew T.</creatorcontrib><creatorcontrib>Brown, Morton B.</creatorcontrib><creatorcontrib>Cassidy, Ruth B.</creatorcontrib><creatorcontrib>Nay, Catherine K.</creatorcontrib><creatorcontrib>Lockwood, Amy L.</creatorcontrib><creatorcontrib>Varban, Oliver A.</creatorcontrib><creatorcontrib>Oral, Elif A.</creatorcontrib><title>Roux-En-Y Gastric Bypass Vs. Sleeve Gastrectomy: Balancing the Risks of Surgery with the Benefits of Weight Loss</title><title>Obesity surgery</title><addtitle>OBES SURG</addtitle><addtitle>Obes Surg</addtitle><description>Background
The purpose of the study was to compare weight loss, metabolic parameters, and postoperative complications in patients undergoing Roux-en-Y gastric bypass (GB) and sleeve gastrectomy (SG).
Methods
We retrospectively studied 30-day postoperative complications as well as change in weight, blood pressure, cholesterol, hemoglobin, hemoglobin A1C, and creatinine from baseline to 2, 6, 12, and 24 months postoperatively in 383 patients undergoing GB and 336 patients undergoing SG at the University of Michigan from January 2008 to November 2013. For a study population which typically has high attrition rates, there were excellent follow-up rates (706/719 at 2 months, 566/719 at 6 months, 519/719 at 12 months, and 382/719 at 24 months).
Results
Baseline characteristics were similar in both groups except for higher weight and BMI in the SG group. The GB group experienced greater total body weight loss at 6, 12, and 24 months (41.9 vs. 34.6 kg at 24 months,
p
< 0.0001). Excess weight loss was 69.7 and 51.7 % following GB and SG respectively at 24 months (
p
< 0.0001). BP improved significantly in both groups. Surgical complication rates were greater after GB (10.1 vs. 3.5 %,
p
= 0.0007) with no significant difference in life-threatening or potentially life-threatening complications.
Conclusions
Weight loss was greater following GB compared to SG at 2 years. The risk for surgical complications was greater following GB. Surgical intervention should be tailored to surgical risk, comorbidities, and desired weight loss.</description><subject>Adult</subject><subject>Comorbidity</subject><subject>Female</subject><subject>Gastrectomy - adverse effects</subject><subject>Gastrectomy - methods</subject><subject>Gastrectomy - statistics & numerical data</subject><subject>Gastric Bypass - adverse effects</subject><subject>Gastric Bypass - methods</subject><subject>Gastric Bypass - statistics & numerical data</subject><subject>Gastrointestinal surgery</subject><subject>Humans</subject><subject>Laparoscopy - adverse effects</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metabolism</subject><subject>Middle Aged</subject><subject>Obesity</subject><subject>Obesity, Morbid - epidemiology</subject><subject>Obesity, Morbid - surgery</subject><subject>Original Contributions</subject><subject>Postoperative Complications - epidemiology</subject><subject>Postoperative Complications - etiology</subject><subject>Retrospective Studies</subject><subject>Risk Assessment</subject><subject>Surgery</subject><subject>Treatment Outcome</subject><subject>Weight control</subject><subject>Weight Loss - physiology</subject><issn>0960-8923</issn><issn>1708-0428</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kV1rFDEUhoModq3-AG8k4I03qfmYSSZeCN1Sq7Ag9BOvQiY92U2dnVmTTHX_velOLVXwIiTwPuc95-RF6DWjB4xS9T4xJnVNKJOEc1kT_gTNmKINoRVvnqIZ1ZKSRnOxh16kdEMpZ5Lz52iPK1GVo2doczqMv8hxT77hE5tyDA7PtxubEr5MB_isA7iFSQGXh_X2A57bzvYu9EucV4BPQ_qe8ODx2RiXELf4Z8irnTKHHnzIO_EKwnKV8WJI6SV65m2X4NX9vY8uPh2fH30mi68nX44OF8RVimbiddP6qq0rqHzLqVJNeXoqAYBTL7XnrZJMKacFvXZWyKqRddVqyQXVnGmxjz5OvpuxXcO1gz5H25lNDGsbt2awwfyt9GFllsOtqVmjhGyKwbt7gzj8GCFlsw7JQVe2h2FMhjVcKiqkqAv69h_0ZhhjX9YrVM11mW1HsYlysfxDBP8wDKPmLk8z5WlKnuYuT8NLzZvHWzxU_AmwAHwCUpH6ksCj1v91_Q1bfKqW</recordid><startdate>20170101</startdate><enddate>20170101</enddate><creator>Lager, Corey J.</creator><creator>Esfandiari, Nazanene H.</creator><creator>Subauste, Angela R.</creator><creator>Kraftson, Andrew T.</creator><creator>Brown, Morton B.</creator><creator>Cassidy, Ruth B.</creator><creator>Nay, Catherine K.</creator><creator>Lockwood, Amy L.</creator><creator>Varban, Oliver A.</creator><creator>Oral, Elif A.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170101</creationdate><title>Roux-En-Y Gastric Bypass Vs. Sleeve Gastrectomy: Balancing the Risks of Surgery with the Benefits of Weight Loss</title><author>Lager, Corey J. ; Esfandiari, Nazanene H. ; Subauste, Angela R. ; Kraftson, Andrew T. ; Brown, Morton B. ; Cassidy, Ruth B. ; Nay, Catherine K. ; Lockwood, Amy L. ; Varban, Oliver A. ; Oral, Elif A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-f98bf4b54e4fb2077854ef06eee20f69f2b76177c930dca3648654b9623092193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Comorbidity</topic><topic>Female</topic><topic>Gastrectomy - adverse effects</topic><topic>Gastrectomy - methods</topic><topic>Gastrectomy - statistics & numerical data</topic><topic>Gastric Bypass - adverse effects</topic><topic>Gastric Bypass - methods</topic><topic>Gastric Bypass - statistics & numerical data</topic><topic>Gastrointestinal surgery</topic><topic>Humans</topic><topic>Laparoscopy - adverse effects</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metabolism</topic><topic>Middle Aged</topic><topic>Obesity</topic><topic>Obesity, Morbid - epidemiology</topic><topic>Obesity, Morbid - surgery</topic><topic>Original Contributions</topic><topic>Postoperative Complications - epidemiology</topic><topic>Postoperative Complications - etiology</topic><topic>Retrospective Studies</topic><topic>Risk Assessment</topic><topic>Surgery</topic><topic>Treatment Outcome</topic><topic>Weight control</topic><topic>Weight Loss - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lager, Corey J.</creatorcontrib><creatorcontrib>Esfandiari, Nazanene H.</creatorcontrib><creatorcontrib>Subauste, Angela R.</creatorcontrib><creatorcontrib>Kraftson, Andrew T.</creatorcontrib><creatorcontrib>Brown, Morton B.</creatorcontrib><creatorcontrib>Cassidy, Ruth B.</creatorcontrib><creatorcontrib>Nay, Catherine K.</creatorcontrib><creatorcontrib>Lockwood, Amy L.</creatorcontrib><creatorcontrib>Varban, Oliver A.</creatorcontrib><creatorcontrib>Oral, Elif A.</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Obesity surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lager, Corey J.</au><au>Esfandiari, Nazanene H.</au><au>Subauste, Angela R.</au><au>Kraftson, Andrew T.</au><au>Brown, Morton B.</au><au>Cassidy, Ruth B.</au><au>Nay, Catherine K.</au><au>Lockwood, Amy L.</au><au>Varban, Oliver A.</au><au>Oral, Elif A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Roux-En-Y Gastric Bypass Vs. Sleeve Gastrectomy: Balancing the Risks of Surgery with the Benefits of Weight Loss</atitle><jtitle>Obesity surgery</jtitle><stitle>OBES SURG</stitle><addtitle>Obes Surg</addtitle><date>2017-01-01</date><risdate>2017</risdate><volume>27</volume><issue>1</issue><spage>154</spage><epage>161</epage><pages>154-161</pages><issn>0960-8923</issn><eissn>1708-0428</eissn><abstract>Background
The purpose of the study was to compare weight loss, metabolic parameters, and postoperative complications in patients undergoing Roux-en-Y gastric bypass (GB) and sleeve gastrectomy (SG).
Methods
We retrospectively studied 30-day postoperative complications as well as change in weight, blood pressure, cholesterol, hemoglobin, hemoglobin A1C, and creatinine from baseline to 2, 6, 12, and 24 months postoperatively in 383 patients undergoing GB and 336 patients undergoing SG at the University of Michigan from January 2008 to November 2013. For a study population which typically has high attrition rates, there were excellent follow-up rates (706/719 at 2 months, 566/719 at 6 months, 519/719 at 12 months, and 382/719 at 24 months).
Results
Baseline characteristics were similar in both groups except for higher weight and BMI in the SG group. The GB group experienced greater total body weight loss at 6, 12, and 24 months (41.9 vs. 34.6 kg at 24 months,
p
< 0.0001). Excess weight loss was 69.7 and 51.7 % following GB and SG respectively at 24 months (
p
< 0.0001). BP improved significantly in both groups. Surgical complication rates were greater after GB (10.1 vs. 3.5 %,
p
= 0.0007) with no significant difference in life-threatening or potentially life-threatening complications.
Conclusions
Weight loss was greater following GB compared to SG at 2 years. The risk for surgical complications was greater following GB. Surgical intervention should be tailored to surgical risk, comorbidities, and desired weight loss.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>27342739</pmid><doi>10.1007/s11695-016-2265-2</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adult Comorbidity Female Gastrectomy - adverse effects Gastrectomy - methods Gastrectomy - statistics & numerical data Gastric Bypass - adverse effects Gastric Bypass - methods Gastric Bypass - statistics & numerical data Gastrointestinal surgery Humans Laparoscopy - adverse effects Male Medicine Medicine & Public Health Metabolism Middle Aged Obesity Obesity, Morbid - epidemiology Obesity, Morbid - surgery Original Contributions Postoperative Complications - epidemiology Postoperative Complications - etiology Retrospective Studies Risk Assessment Surgery Treatment Outcome Weight control Weight Loss - physiology |
| title | Roux-En-Y Gastric Bypass Vs. Sleeve Gastrectomy: Balancing the Risks of Surgery with the Benefits of Weight Loss |
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