Implementation of next generation sequencing into pediatric hematology-oncology practice: moving beyond actionable alterations

Molecular characterization has the potential to advance the management of pediatric cancer and high-risk hematologic disease. The clinical integration of genome sequencing into standard clinical practice has been limited and the potential utility of genome sequencing to identify clinically impactful...

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Veröffentlicht in:	Genome medicine 2016-12, Vol.8 (1), p.133-133, Article 133
Hauptverfasser:	Oberg, Jennifer A, Glade Bender, Julia L, Sulis, Maria Luisa, Pendrick, Danielle, Sireci, Anthony N, Hsiao, Susan J, Turk, Andrew T, Dela Cruz, Filemon S, Hibshoosh, Hanina, Remotti, Helen, Zylber, Rebecca J, Pang, Jiuhong, Diolaiti, Daniel, Koval, Carrie, Andrews, Stuart J, Garvin, James H, Yamashiro, Darrell J, Chung, Wendy K, Emerson, Stephen G, Nagy, Peter L, Mansukhani, Mahesh M, Kung, Andrew L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Cancer in children Care and treatment Child Child, Preschool Exome sequencing Female Hematologic Diseases - genetics Hematologic Diseases - metabolism High-Throughput Nucleotide Sequencing - methods Humans Infant Infant, Newborn Male Methods Neoplasms - genetics Neoplasms - metabolism Oncogene Proteins, Fusion - genetics Oncogene Proteins, Fusion - metabolism Patient outcomes RNA, Neoplasm - genetics RNA, Neoplasm - metabolism
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