Atypical presentation of anti-GBM nephritis in a 90-year-old patient
A 90-year-old woman who had bloody diarrhoea, nausea, weakness and reduced urine output was found to have acute kidney injury. Her inflammatory markers were raised and her chest X-ray suggested an inflammatory process. She was initially suspected to have acute kidney injury secondary to dehydration...
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| Veröffentlicht in: | BMJ case reports 2016-11, Vol.2016, p.bcr2016217990 |
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| creator | Okiro, Julie Omolola Ebad, Chaudhry Adeel Khan, Amjad Zaman |
| description | A 90-year-old woman who had bloody diarrhoea, nausea, weakness and reduced urine output was found to have acute kidney injury. Her inflammatory markers were raised and her chest X-ray suggested an inflammatory process. She was initially suspected to have acute kidney injury secondary to dehydration and sepsis but when her autoimmune screen returned positive for antiglomerular basement membrane antibodies our diagnosis and management strategy was reconsidered. This is a case report of Goodpasture disease presenting in an elderly patient. |
| doi_str_mv | 10.1136/bcr-2016-217990 |
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Her inflammatory markers were raised and her chest X-ray suggested an inflammatory process. She was initially suspected to have acute kidney injury secondary to dehydration and sepsis but when her autoimmune screen returned positive for antiglomerular basement membrane antibodies our diagnosis and management strategy was reconsidered. This is a case report of Goodpasture disease presenting in an elderly patient.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2016-217990</identifier><identifier>PMID: 27899391</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>80 years ; Acute Kidney Injury - diagnosis ; Age groups ; Aged, 80 and over ; Albuterol - therapeutic use ; Anti-Bacterial Agents - administration & dosage ; Anti-Glomerular Basement Membrane Disease - diagnosis ; Anti-Glomerular Basement Membrane Disease - physiopathology ; Anti-Glomerular Basement Membrane Disease - therapy ; Bronchodilator Agents - therapeutic use ; Catheters ; Ceftriaxone - administration & dosage ; Cytokines ; Diarrhea ; Diarrhea - etiology ; Disease ; Electrolytes ; Esomeprazole - administration & dosage ; Europe (West) ; Family medical history ; Fatal Outcome ; Female ; Gangrene ; Humans ; Immunoglobulins ; Kidneys ; Metabolism ; Nausea - etiology ; Older people ; Palliative Care ; Patient Comfort ; Patients ; Plasma Exchange ; Pneumonia ; Potassium ; Proton Pump Inhibitors - administration & dosage ; Unusual Presentation of More Common Disease/Injury ; Urine ; White</subject><ispartof>BMJ case reports, 2016-11, Vol.2016, p.bcr2016217990</ispartof><rights>2016 BMJ Publishing Group Ltd</rights><rights>2016 BMJ Publishing Group Ltd.</rights><rights>Copyright: 2016 2016 BMJ Publishing Group Ltd</rights><rights>2016 BMJ Publishing Group Ltd 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b3710-223bb674d0a69d8a330edb420bff1aa34e13b176215e029cd6d16b3332703b333</citedby><cites>FETCH-LOGICAL-b3710-223bb674d0a69d8a330edb420bff1aa34e13b176215e029cd6d16b3332703b333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174896/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174896/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27899391$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Okiro, Julie Omolola</creatorcontrib><creatorcontrib>Ebad, Chaudhry Adeel</creatorcontrib><creatorcontrib>Khan, Amjad Zaman</creatorcontrib><title>Atypical presentation of anti-GBM nephritis in a 90-year-old patient</title><title>BMJ case reports</title><addtitle>BMJ Case Rep</addtitle><description>A 90-year-old woman who had bloody diarrhoea, nausea, weakness and reduced urine output was found to have acute kidney injury. Her inflammatory markers were raised and her chest X-ray suggested an inflammatory process. She was initially suspected to have acute kidney injury secondary to dehydration and sepsis but when her autoimmune screen returned positive for antiglomerular basement membrane antibodies our diagnosis and management strategy was reconsidered. This is a case report of Goodpasture disease presenting in an elderly patient.</description><subject>80 years</subject><subject>Acute Kidney Injury - diagnosis</subject><subject>Age groups</subject><subject>Aged, 80 and over</subject><subject>Albuterol - therapeutic use</subject><subject>Anti-Bacterial Agents - administration & dosage</subject><subject>Anti-Glomerular Basement Membrane Disease - diagnosis</subject><subject>Anti-Glomerular Basement Membrane Disease - physiopathology</subject><subject>Anti-Glomerular Basement Membrane Disease - therapy</subject><subject>Bronchodilator Agents - therapeutic use</subject><subject>Catheters</subject><subject>Ceftriaxone - administration & dosage</subject><subject>Cytokines</subject><subject>Diarrhea</subject><subject>Diarrhea - etiology</subject><subject>Disease</subject><subject>Electrolytes</subject><subject>Esomeprazole - administration & dosage</subject><subject>Europe (West)</subject><subject>Family medical history</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Gangrene</subject><subject>Humans</subject><subject>Immunoglobulins</subject><subject>Kidneys</subject><subject>Metabolism</subject><subject>Nausea - etiology</subject><subject>Older people</subject><subject>Palliative Care</subject><subject>Patient Comfort</subject><subject>Patients</subject><subject>Plasma Exchange</subject><subject>Pneumonia</subject><subject>Potassium</subject><subject>Proton Pump Inhibitors - administration & dosage</subject><subject>Unusual Presentation of More Common Disease/Injury</subject><subject>Urine</subject><subject>White</subject><issn>1757-790X</issn><issn>1757-790X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkc9LBCEUxyWKiurcLQa6RGD51NHxEvS7oOhS0E10ximX2XHS2WD_-1y2orrk5Ql-3vf5-CC0C-QIgIljW0dMCQhMQSpFVtAmyFJiqcjz6o_7BtpJaULyYcArztbRBpWVUkzBJro4HeeDr01XDNEl149m9KEvQluYfvT4-uy-6N3wGv3oU-H7whSK4LkzEYeuKYZM555ttNaaLrmdz7qFnq4uH89v8N3D9e356R22TALBlDJrheQNMUI1lWGMuMZySmzbgjGMO2AWpKBQOkJV3YgGhGWMUUnYom6hk2XuMLNT19R5dDSdHqKfmjjXwXj9-6X3r_olvOsSJK-UyAEHnwExvM1cGvXUp9p1neldmCUNFS8pV0rwjO7_QSdhFvu83oLilQDGykwdL6k6hpSia78_A0QvJOksSS8k6aWk3LH3c4dv_ktJBg6XgJ1O_k37AGJ1mLE</recordid><startdate>20161129</startdate><enddate>20161129</enddate><creator>Okiro, Julie Omolola</creator><creator>Ebad, Chaudhry Adeel</creator><creator>Khan, Amjad Zaman</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20161129</creationdate><title>Atypical presentation of anti-GBM nephritis in a 90-year-old patient</title><author>Okiro, Julie Omolola ; Ebad, Chaudhry Adeel ; Khan, Amjad Zaman</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b3710-223bb674d0a69d8a330edb420bff1aa34e13b176215e029cd6d16b3332703b333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>80 years</topic><topic>Acute Kidney Injury - diagnosis</topic><topic>Age groups</topic><topic>Aged, 80 and over</topic><topic>Albuterol - therapeutic use</topic><topic>Anti-Bacterial Agents - administration & dosage</topic><topic>Anti-Glomerular Basement Membrane Disease - diagnosis</topic><topic>Anti-Glomerular Basement Membrane Disease - physiopathology</topic><topic>Anti-Glomerular Basement Membrane Disease - therapy</topic><topic>Bronchodilator Agents - therapeutic use</topic><topic>Catheters</topic><topic>Ceftriaxone - administration & dosage</topic><topic>Cytokines</topic><topic>Diarrhea</topic><topic>Diarrhea - etiology</topic><topic>Disease</topic><topic>Electrolytes</topic><topic>Esomeprazole - administration & dosage</topic><topic>Europe (West)</topic><topic>Family medical history</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Gangrene</topic><topic>Humans</topic><topic>Immunoglobulins</topic><topic>Kidneys</topic><topic>Metabolism</topic><topic>Nausea - etiology</topic><topic>Older people</topic><topic>Palliative Care</topic><topic>Patient Comfort</topic><topic>Patients</topic><topic>Plasma Exchange</topic><topic>Pneumonia</topic><topic>Potassium</topic><topic>Proton Pump Inhibitors - administration & dosage</topic><topic>Unusual Presentation of More Common Disease/Injury</topic><topic>Urine</topic><topic>White</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Okiro, Julie Omolola</creatorcontrib><creatorcontrib>Ebad, Chaudhry Adeel</creatorcontrib><creatorcontrib>Khan, Amjad Zaman</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Okiro, Julie Omolola</au><au>Ebad, Chaudhry Adeel</au><au>Khan, Amjad Zaman</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Atypical presentation of anti-GBM nephritis in a 90-year-old patient</atitle><jtitle>BMJ case reports</jtitle><addtitle>BMJ Case Rep</addtitle><date>2016-11-29</date><risdate>2016</risdate><volume>2016</volume><spage>bcr2016217990</spage><pages>bcr2016217990-</pages><issn>1757-790X</issn><eissn>1757-790X</eissn><abstract>A 90-year-old woman who had bloody diarrhoea, nausea, weakness and reduced urine output was found to have acute kidney injury. Her inflammatory markers were raised and her chest X-ray suggested an inflammatory process. She was initially suspected to have acute kidney injury secondary to dehydration and sepsis but when her autoimmune screen returned positive for antiglomerular basement membrane antibodies our diagnosis and management strategy was reconsidered. This is a case report of Goodpasture disease presenting in an elderly patient.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>27899391</pmid><doi>10.1136/bcr-2016-217990</doi><oa>free_for_read</oa></addata></record> |
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| subjects | 80 years Acute Kidney Injury - diagnosis Age groups Aged, 80 and over Albuterol - therapeutic use Anti-Bacterial Agents - administration & dosage Anti-Glomerular Basement Membrane Disease - diagnosis Anti-Glomerular Basement Membrane Disease - physiopathology Anti-Glomerular Basement Membrane Disease - therapy Bronchodilator Agents - therapeutic use Catheters Ceftriaxone - administration & dosage Cytokines Diarrhea Diarrhea - etiology Disease Electrolytes Esomeprazole - administration & dosage Europe (West) Family medical history Fatal Outcome Female Gangrene Humans Immunoglobulins Kidneys Metabolism Nausea - etiology Older people Palliative Care Patient Comfort Patients Plasma Exchange Pneumonia Potassium Proton Pump Inhibitors - administration & dosage Unusual Presentation of More Common Disease/Injury Urine White |
| title | Atypical presentation of anti-GBM nephritis in a 90-year-old patient |
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