Antigen presentation by B cells guides programming of memory CD4 T cell responses to a TLR4-agonist containing vaccine

The contribution of B cells to immunity against many infectious diseases is unquestionably important and well characterized. Here we sought to determine the role of B cells in the induction of T helper 1 (T H 1) CD4+ T cells upon vaccination with a TB antigen combined with a TLR4 agonist. We used B...

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Veröffentlicht in:European journal of immunology 2016-11, Vol.46 (12), p.2719-2729
Hauptverfasser: Cauwelaert, Natasha Dubois, Baldwin, Susan L., Orr, Mark T., Desbien, Anthony L., Gage, Emily, Hofmeyer, Kimberly A., Coler, Rhea N.
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Sprache:eng
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