Nuclear constriction segregates mobile nuclear proteins away from chromatin

As a cell squeezes its nucleus through adjacent tissue, penetrates a basement membrane, or enters a small blood capillary, chromatin density and nuclear factors could in principle be physically perturbed. Here, in cancer cell migration through rigid micropores and in passive pulling into micropipett...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular biology of the cell 2016-12, Vol.27 (25), p.4011-4020
Hauptverfasser:	Irianto, Jerome, Pfeifer, Charlotte R, Bennett, Rachel R, Xia, Yuntao, Ivanovska, Irena L, Liu, Andrea J, Greenberg, Roger A, Discher, Dennis E
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Cell Movement - physiology Cell Nucleus - metabolism Cell Nucleus - physiology Chromatin - metabolism Euchromatin - metabolism Heterochromatin - metabolism Histones - metabolism Humans Models, Biological Nuclear Envelope - metabolism Nuclear Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!