Impact of oral contraceptive pills on central corneal thickness in young women
Objectives: Hormonal changes during oral contraceptive pill (OCP) use may affect central corneal thickness (CCT) values. We aimed to evaluate the impact of OCP use on CCT values in healthy young women. Materials and Methods: Fifty women subjects who use OCP for contraception (Group 1) and forty cont...
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| Veröffentlicht in: | Indian journal of pharmacology 2016-11, Vol.48 (6), p.665-668 |
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| creator | Kurtul, Bengi Inal, Besime Ozer, Pinar Kabatas, Emrah |
| description | Objectives: Hormonal changes during oral contraceptive pill (OCP) use may affect central corneal thickness (CCT) values. We aimed to evaluate the impact of OCP use on CCT values in healthy young women.
Materials and Methods: Fifty women subjects who use OCP for contraception (Group 1) and forty control subjects (Group 2) who do not use OCP were included in this prospective study. None of the patients had any history of systemic or ocular diseases. The CCT values measured by ultrasonic pachymeter (Nidek US-4000 Echoscan, Japan) and the intraocular pressure (IOP) values were measured by noncontact tonometer (Reichert 7 CR Corneal Response Technology, USA) at the time of admission to our clinic. The demographic findings and body mass index (BMI) scores of participants were also recorded.
Results: The mean ages were 32.8 ± 5.6 for OCP + patients (Group 1) and 31.3 ± 6.9 for OCP-patients (Group 2) (P = 0.28). The mean CCT values were significantly higher in Group 1 when compared to that of the Group 2 (540.9 ± 30.4 μm and 519.6 ± 35.6 μm, respectively) (P = 0.003). The mean IOP value was 14.3 ± 2.5 mmHg in Group 1 and 14.4 ± 2.7 mmHg in Group 2 (P = 0.96). The mean BMI scores were 24.4 ± 5.8 kg/m2 in Group 1 and 24.6 ± 3.5 kg/m2 in Group 2 (P = 0.83).
Conclusion: Our findings revealed that CCT values were significantly higher in patients with OCP use. Ophthalmologists should be aware of potential elevated CCT levels in these patients. |
| doi_str_mv | 10.4103/0253-7613.194860 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5155467</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A472313205</galeid><sourcerecordid>A472313205</sourcerecordid><originalsourceid>FETCH-LOGICAL-c603e-e56af4e055aa87a3fb3c159758acf8aba9bbfcd0c0501af7cdfdaf9bd7fce5ba3</originalsourceid><addsrcrecordid>eNptkkFr3DAQhUVpaTZp7z0VQy-9eCtZlmxdCiGkTSC0FNqzkOXRRllbciU7S_59ZbxZsmXRQWjmm8fo8RD6QPC6JJh-wQWjecUJXRNR1hy_QisiRJ3TipHXaHVon6HzGB9wepeCv0VnRY05J7hcoR-3_aD0mHmT-aC6THs3BqVhGO0jZIPtuph5l2mYy3M7OEj3eG_11kGMmXXZk5_cJtv5Htw79MaoLsL7_X2B_ny7_n11k9_9_H57dXmXa44p5MC4MiVgxpSqK0VNQzVhomK10qZWjRJNY3SLNWaYKFPp1rTKiKatjAbWKHqBvi66w9T00O7Xk0OwvQpP0isrjzvO3suNf5SMMFbyKgl83gsE_3eCOMreRg1dpxz4KUpSM15zxgRP6Kf_0Ac_BZe-J4nAWOCCJ58P1EZ1IK0zfvZxFpWXZVVQQgs8U_kJagMO0pLegbGpfMSvT_DptNBbfXIALwM6-BgDmIMnBMs5M3IOhZxDIZfMpJGPL708DDyHJAG_FmDnuxFC3HbTDoJM7Nb53ZFw_kJYcs7kEi_pjZzjJZ_jRf8BnSjYMA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1900902625</pqid></control><display><type>article</type><title>Impact of oral contraceptive pills on central corneal thickness in young women</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central Open Access</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Kurtul, Bengi ; Inal, Besime ; Ozer, Pinar ; Kabatas, Emrah</creator><creatorcontrib>Kurtul, Bengi ; Inal, Besime ; Ozer, Pinar ; Kabatas, Emrah</creatorcontrib><description>Objectives: Hormonal changes during oral contraceptive pill (OCP) use may affect central corneal thickness (CCT) values. We aimed to evaluate the impact of OCP use on CCT values in healthy young women.
Materials and Methods: Fifty women subjects who use OCP for contraception (Group 1) and forty control subjects (Group 2) who do not use OCP were included in this prospective study. None of the patients had any history of systemic or ocular diseases. The CCT values measured by ultrasonic pachymeter (Nidek US-4000 Echoscan, Japan) and the intraocular pressure (IOP) values were measured by noncontact tonometer (Reichert 7 CR Corneal Response Technology, USA) at the time of admission to our clinic. The demographic findings and body mass index (BMI) scores of participants were also recorded.
Results: The mean ages were 32.8 ± 5.6 for OCP + patients (Group 1) and 31.3 ± 6.9 for OCP-patients (Group 2) (P = 0.28). The mean CCT values were significantly higher in Group 1 when compared to that of the Group 2 (540.9 ± 30.4 μm and 519.6 ± 35.6 μm, respectively) (P = 0.003). The mean IOP value was 14.3 ± 2.5 mmHg in Group 1 and 14.4 ± 2.7 mmHg in Group 2 (P = 0.96). The mean BMI scores were 24.4 ± 5.8 kg/m2 in Group 1 and 24.6 ± 3.5 kg/m2 in Group 2 (P = 0.83).
Conclusion: Our findings revealed that CCT values were significantly higher in patients with OCP use. Ophthalmologists should be aware of potential elevated CCT levels in these patients.</description><identifier>ISSN: 0253-7613</identifier><identifier>EISSN: 1998-3751</identifier><identifier>DOI: 10.4103/0253-7613.194860</identifier><identifier>PMID: 28066104</identifier><language>eng</language><publisher>India: Wolters Kluwer India Pvt. Ltd</publisher><subject>Adult ; Birth control ; Body mass index ; Children & youth ; Childrens health ; Contraceptives, Oral, Combined - administration & dosage ; Contraceptives, Oral, Combined - adverse effects ; Cornea ; Cornea - drug effects ; Cornea - pathology ; Cornea - physiology ; Corneal Pachymetry - methods ; Dosage and administration ; Drug therapy ; Female ; Glaucoma ; Health aspects ; Hospitals ; Humans ; Intraocular Pressure - drug effects ; Intraocular Pressure - physiology ; Menstruation ; Middle Aged ; Obesity ; Oral contraceptives ; Patient outcomes ; Pregnancy ; Prospective Studies ; Statistical analysis ; Tonometry, Ocular - methods ; Womens health ; Young adults ; Young women</subject><ispartof>Indian journal of pharmacology, 2016-11, Vol.48 (6), p.665-668</ispartof><rights>COPYRIGHT 2016 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright Medknow Publications & Media Pvt. Ltd. Nov/Dec 2016</rights><rights>Copyright: © Indian Journal of Pharmacology 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c603e-e56af4e055aa87a3fb3c159758acf8aba9bbfcd0c0501af7cdfdaf9bd7fce5ba3</citedby><cites>FETCH-LOGICAL-c603e-e56af4e055aa87a3fb3c159758acf8aba9bbfcd0c0501af7cdfdaf9bd7fce5ba3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155467/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155467/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28066104$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kurtul, Bengi</creatorcontrib><creatorcontrib>Inal, Besime</creatorcontrib><creatorcontrib>Ozer, Pinar</creatorcontrib><creatorcontrib>Kabatas, Emrah</creatorcontrib><title>Impact of oral contraceptive pills on central corneal thickness in young women</title><title>Indian journal of pharmacology</title><addtitle>Indian J Pharmacol</addtitle><description>Objectives: Hormonal changes during oral contraceptive pill (OCP) use may affect central corneal thickness (CCT) values. We aimed to evaluate the impact of OCP use on CCT values in healthy young women.
Materials and Methods: Fifty women subjects who use OCP for contraception (Group 1) and forty control subjects (Group 2) who do not use OCP were included in this prospective study. None of the patients had any history of systemic or ocular diseases. The CCT values measured by ultrasonic pachymeter (Nidek US-4000 Echoscan, Japan) and the intraocular pressure (IOP) values were measured by noncontact tonometer (Reichert 7 CR Corneal Response Technology, USA) at the time of admission to our clinic. The demographic findings and body mass index (BMI) scores of participants were also recorded.
Results: The mean ages were 32.8 ± 5.6 for OCP + patients (Group 1) and 31.3 ± 6.9 for OCP-patients (Group 2) (P = 0.28). The mean CCT values were significantly higher in Group 1 when compared to that of the Group 2 (540.9 ± 30.4 μm and 519.6 ± 35.6 μm, respectively) (P = 0.003). The mean IOP value was 14.3 ± 2.5 mmHg in Group 1 and 14.4 ± 2.7 mmHg in Group 2 (P = 0.96). The mean BMI scores were 24.4 ± 5.8 kg/m2 in Group 1 and 24.6 ± 3.5 kg/m2 in Group 2 (P = 0.83).
Conclusion: Our findings revealed that CCT values were significantly higher in patients with OCP use. Ophthalmologists should be aware of potential elevated CCT levels in these patients.</description><subject>Adult</subject><subject>Birth control</subject><subject>Body mass index</subject><subject>Children & youth</subject><subject>Childrens health</subject><subject>Contraceptives, Oral, Combined - administration & dosage</subject><subject>Contraceptives, Oral, Combined - adverse effects</subject><subject>Cornea</subject><subject>Cornea - drug effects</subject><subject>Cornea - pathology</subject><subject>Cornea - physiology</subject><subject>Corneal Pachymetry - methods</subject><subject>Dosage and administration</subject><subject>Drug therapy</subject><subject>Female</subject><subject>Glaucoma</subject><subject>Health aspects</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Intraocular Pressure - drug effects</subject><subject>Intraocular Pressure - physiology</subject><subject>Menstruation</subject><subject>Middle Aged</subject><subject>Obesity</subject><subject>Oral contraceptives</subject><subject>Patient outcomes</subject><subject>Pregnancy</subject><subject>Prospective Studies</subject><subject>Statistical analysis</subject><subject>Tonometry, Ocular - methods</subject><subject>Womens health</subject><subject>Young adults</subject><subject>Young women</subject><issn>0253-7613</issn><issn>1998-3751</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkkFr3DAQhUVpaTZp7z0VQy-9eCtZlmxdCiGkTSC0FNqzkOXRRllbciU7S_59ZbxZsmXRQWjmm8fo8RD6QPC6JJh-wQWjecUJXRNR1hy_QisiRJ3TipHXaHVon6HzGB9wepeCv0VnRY05J7hcoR-3_aD0mHmT-aC6THs3BqVhGO0jZIPtuph5l2mYy3M7OEj3eG_11kGMmXXZk5_cJtv5Htw79MaoLsL7_X2B_ny7_n11k9_9_H57dXmXa44p5MC4MiVgxpSqK0VNQzVhomK10qZWjRJNY3SLNWaYKFPp1rTKiKatjAbWKHqBvi66w9T00O7Xk0OwvQpP0isrjzvO3suNf5SMMFbyKgl83gsE_3eCOMreRg1dpxz4KUpSM15zxgRP6Kf_0Ac_BZe-J4nAWOCCJ58P1EZ1IK0zfvZxFpWXZVVQQgs8U_kJagMO0pLegbGpfMSvT_DptNBbfXIALwM6-BgDmIMnBMs5M3IOhZxDIZfMpJGPL708DDyHJAG_FmDnuxFC3HbTDoJM7Nb53ZFw_kJYcs7kEi_pjZzjJZ_jRf8BnSjYMA</recordid><startdate>20161101</startdate><enddate>20161101</enddate><creator>Kurtul, Bengi</creator><creator>Inal, Besime</creator><creator>Ozer, Pinar</creator><creator>Kabatas, Emrah</creator><general>Wolters Kluwer India Pvt. 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Kabatas, Emrah</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c603e-e56af4e055aa87a3fb3c159758acf8aba9bbfcd0c0501af7cdfdaf9bd7fce5ba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Birth control</topic><topic>Body mass index</topic><topic>Children & youth</topic><topic>Childrens health</topic><topic>Contraceptives, Oral, Combined - administration & dosage</topic><topic>Contraceptives, Oral, Combined - adverse effects</topic><topic>Cornea</topic><topic>Cornea - drug effects</topic><topic>Cornea - pathology</topic><topic>Cornea - physiology</topic><topic>Corneal Pachymetry - methods</topic><topic>Dosage and administration</topic><topic>Drug therapy</topic><topic>Female</topic><topic>Glaucoma</topic><topic>Health aspects</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Intraocular Pressure - drug effects</topic><topic>Intraocular Pressure - physiology</topic><topic>Menstruation</topic><topic>Middle Aged</topic><topic>Obesity</topic><topic>Oral contraceptives</topic><topic>Patient outcomes</topic><topic>Pregnancy</topic><topic>Prospective Studies</topic><topic>Statistical analysis</topic><topic>Tonometry, Ocular - methods</topic><topic>Womens health</topic><topic>Young adults</topic><topic>Young women</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kurtul, Bengi</creatorcontrib><creatorcontrib>Inal, Besime</creatorcontrib><creatorcontrib>Ozer, Pinar</creatorcontrib><creatorcontrib>Kabatas, Emrah</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Indian journal of pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kurtul, Bengi</au><au>Inal, Besime</au><au>Ozer, Pinar</au><au>Kabatas, Emrah</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of oral contraceptive pills on central corneal thickness in young women</atitle><jtitle>Indian journal of pharmacology</jtitle><addtitle>Indian J Pharmacol</addtitle><date>2016-11-01</date><risdate>2016</risdate><volume>48</volume><issue>6</issue><spage>665</spage><epage>668</epage><pages>665-668</pages><issn>0253-7613</issn><eissn>1998-3751</eissn><abstract>Objectives: Hormonal changes during oral contraceptive pill (OCP) use may affect central corneal thickness (CCT) values. We aimed to evaluate the impact of OCP use on CCT values in healthy young women.
Materials and Methods: Fifty women subjects who use OCP for contraception (Group 1) and forty control subjects (Group 2) who do not use OCP were included in this prospective study. None of the patients had any history of systemic or ocular diseases. The CCT values measured by ultrasonic pachymeter (Nidek US-4000 Echoscan, Japan) and the intraocular pressure (IOP) values were measured by noncontact tonometer (Reichert 7 CR Corneal Response Technology, USA) at the time of admission to our clinic. The demographic findings and body mass index (BMI) scores of participants were also recorded.
Results: The mean ages were 32.8 ± 5.6 for OCP + patients (Group 1) and 31.3 ± 6.9 for OCP-patients (Group 2) (P = 0.28). The mean CCT values were significantly higher in Group 1 when compared to that of the Group 2 (540.9 ± 30.4 μm and 519.6 ± 35.6 μm, respectively) (P = 0.003). The mean IOP value was 14.3 ± 2.5 mmHg in Group 1 and 14.4 ± 2.7 mmHg in Group 2 (P = 0.96). The mean BMI scores were 24.4 ± 5.8 kg/m2 in Group 1 and 24.6 ± 3.5 kg/m2 in Group 2 (P = 0.83).
Conclusion: Our findings revealed that CCT values were significantly higher in patients with OCP use. Ophthalmologists should be aware of potential elevated CCT levels in these patients.</abstract><cop>India</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><pmid>28066104</pmid><doi>10.4103/0253-7613.194860</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Adult Birth control Body mass index Children & youth Childrens health Contraceptives, Oral, Combined - administration & dosage Contraceptives, Oral, Combined - adverse effects Cornea Cornea - drug effects Cornea - pathology Cornea - physiology Corneal Pachymetry - methods Dosage and administration Drug therapy Female Glaucoma Health aspects Hospitals Humans Intraocular Pressure - drug effects Intraocular Pressure - physiology Menstruation Middle Aged Obesity Oral contraceptives Patient outcomes Pregnancy Prospective Studies Statistical analysis Tonometry, Ocular - methods Womens health Young adults Young women |
| title | Impact of oral contraceptive pills on central corneal thickness in young women |
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