What does PD-L1 positive or negative mean?

Expression of the programmed death-1 (PD-1) ligand 1 (PD-L1) is used to select patients and analyze responses to anti-PD-1/L1 antibodies. The expression of PD-L1 is regulated in different ways, which leads to a different significance of its presence or absence. PD-L1 positivity may be a result of ge...

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Veröffentlicht in:	The Journal of experimental medicine 2016-12, Vol.213 (13), p.2835-2840
Hauptverfasser:	Ribas, Antoni, Hu-Lieskovan, Siwen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B7-H1 Antigen - genetics B7-H1 Antigen - immunology Humans Neoplasm Proteins - genetics Neoplasm Proteins - immunology Neoplasms - genetics Neoplasms - immunology Neoplasms - pathology Programmed Cell Death 1 Receptor - genetics Programmed Cell Death 1 Receptor - immunology Reviews T-Lymphocytes - immunology T-Lymphocytes - pathology
Online-Zugang:	Volltext
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