Gait function and locus coeruleus Lewy body pathology in 51 Parkinson's disease patients

Abstract Introduction Gait impairment in Parkinson's Disease (PD) is often severely disabling, yet frequently remains refractory to treatment. The locus coeruleus (LC) has diffuse noradrenergic projections that are thought to play a role in gait function. Enhancement of norepinephrine transmiss...

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Veröffentlicht in:	Parkinsonism & related disorders 2016-12, Vol.33, p.102-106
Hauptverfasser:	Mills, Kelly A, Mari, Zoltan, Bakker, Catherine, Johnson, Vanessa, Pontone, Gregory M, Pantelyat, Alexander, Troncoso, Juan C, Pletnikova, Olga, Dawson, Ted M, Rosenthal, Liana S
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Autopsy Female Gait Gait Disorders, Neurologic - etiology Humans Lewy Bodies - pathology Locus coeruleus Locus Coeruleus - pathology Male Middle Aged Neurology Parkinson Disease - complications Parkinson Disease - pathology Parkinson's disease Pathology Severity of Illness Index Statistics, Nonparametric
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