Transcriptional response of yeast to aflatoxin B1: recombinational repair involving RAD51 and RAD1

The potent carcinogen aflatoxin B(1) is a weak mutagen but a strong recombinagen in Saccharomyces cerevisiae. Aflatoxin B(1) exposure greatly increases frequencies of both heteroallelic recombination and chromosomal translocations. We analyzed the gene expression pattern of diploid cells exposed to...

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Veröffentlicht in:	Molecular biology of the cell 2004-09, Vol.15 (9), p.4321-4336
Hauptverfasser:	Keller-Seitz, Monika U, Certa, Ulrich, Sengstag, Christian, Würgler, Friedrich E, Sun, Mingzeng, Fasullo, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - genetics Aflatoxin B1 - toxicity Base Sequence DNA Damage DNA Repair - genetics DNA Repair Enzymes DNA, Fungal - genetics DNA-Binding Proteins - genetics Endonucleases - genetics Genes, Fungal - drug effects Models, Biological Mutagens - toxicity Mutation Rad51 Recombinase Recombination, Genetic - drug effects Saccharomyces cerevisiae - drug effects Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins - genetics Transcription, Genetic - drug effects Translocation, Genetic - drug effects
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