Bromomethylthioindole Inspired Carbazole Hybrids as Promising Class of Anti-MRSA Agents

Series of N-substituted carbazole analogues bearing an indole ring were synthesized as anti-methicillin-resistant Staphylococcus aureus (MRSA) agents from a molecular hybridization approach. The representative compound 19 showed an MIC = 1 μg/mL against a panel of MRSA clinical isolates as it posses...

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Veröffentlicht in:	ACS medicinal chemistry letters 2016-12, Vol.7 (12), p.1191-1196
Hauptverfasser:	Cheng, Chia-Yi, Chang, Chun-Ping, Lauderdale, Tsai-Ling Yang, Yu, Guann-Yi, Lee, Jinq-Chyi, Jhang, Yi-Wun, Wu, Chien-Huang, Ke, Yi-Yu, Sadani, Amit A, Yeh, Ching-Fang, Huang, I-Wen, Kuo, Yi-Ping, Tsai, De-Jiun, Yeh, Teng-Kuang, Tseng, Chen-Tso, Song, Jen-Shin, Liu, Yu-Wei, Tsou, Lun K, Shia, Kak-Shan
Format:	Artikel
Sprache:	eng
Schlagworte:	Letter
Online-Zugang:	Volltext
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