Oral Cnm-positive Streptococcus Mutans Expressing Collagen Binding Activity is a Risk Factor for Cerebral Microbleeds and Cognitive Impairment

Cerebral microbleeds (CMBs) are an important risk factor for stroke and dementia. We have shown that the collagen binding surface Cnm protein expressed on cnm -positive Streptococcus mutans is involved in the development of CMBs. However, whether the collagen binding activity of cnm -positive S. mut...

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Veröffentlicht in:	Scientific reports 2016-12, Vol.6 (1), p.38561-38561, Article 38561
Hauptverfasser:	Watanabe, Isao, Kuriyama, Nagato, Miyatani, Fumitaro, Nomura, Ryota, Naka, Shuhei, Nakano, Kazuhiko, Ihara, Masafumi, Iwai, Komei, Matsui, Daisuke, Ozaki, Etsuko, Koyama, Teruhide, Nishigaki, Masaru, Yamamoto, Toshiro, Tamura, Aiko, Mizuno, Toshiki, Akazawa, Kentaro, Takada, Akihiro, Takeda, Kazuo, Yamada, Kei, Nakagawa, Masanori, Tanaka, Tokutaro, Kanamura, Narisato, Friedland, Robert P., Watanabe, Yoshiyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	692/499 692/617 Adhesins, Bacterial - metabolism Aged Carrier Proteins - metabolism Cerebral Hemorrhage - complications Cerebral Hemorrhage - microbiology Cognitive ability Cognitive Dysfunction - complications Cognitive Dysfunction - microbiology Collagen Collagen - metabolism Dementia Dementia disorders Female Humanities and Social Sciences Humans Magnetic Resonance Imaging Male Mouth - microbiology multidisciplinary Odds Ratio Polymerase chain reaction Protein Binding Risk Factors Saliva Science Streptococcus Streptococcus infections Streptococcus mutans - metabolism Stroke
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