Surfactant-Stripped Frozen Pheophytin Micelles for Multimodal Gut Imaging

Surfactant-Stripped Frozen Pheophytin Micelles for Multimodal Gut Imaging

Edible, surfactant‐stripped, frozen micelles are formed from pheophytin (demetallated chlorophyll), a pigment that is naturally consumed in human diets. Pheophytin nanoparticles pass completely and safely through the gastrointestinal tract and enable trimodal gut contrast imaging via photoacoustic,...

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Veröffentlicht in:Advanced materials (Weinheim) 2016-10, Vol.28 (38), p.8524-8530
Hauptverfasser: Zhang, Yumiao, Wang, Depeng, Goel, Shreya, Sun, Boyang, Chitgupi, Upendra, Geng, Jumin, Sun, Haiyan, Barnhart, Todd E., Cai, Weibo, Xia, Jun, Lovell, Jonathan F.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Chlorophyll
Consumption
Diets
Edible
Female
Freezing
frozen micelles
gut imaging
Imaging
Intestines
Mice
Mice, Inbred ICR
Micelles
Multimodal Imaging
Nanoparticles
pheophytin
Pheophytins - chemistry
Surface-Active Agents
Tomography
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Beschreibung
Zusammenfassung:Edible, surfactant‐stripped, frozen micelles are formed from pheophytin (demetallated chlorophyll), a pigment that is naturally consumed in human diets. Pheophytin nanoparticles pass completely and safely through the gastrointestinal tract and enable trimodal gut contrast imaging via photoacoustic, fluorescence, and positron emission tomography techniques.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201602373