Evolving practice pattern changes and outcomes in the era of hybrid aortic arch repair

Objective The role of hybrid repair in the management of aortic arch pathology, and long-term outcomes with these techniques, remains uncertain. We report a decade of experience with hybrid arch repair (HAR) and assess institutional practice patterns with regard to the use of hybrid and open techniq...

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Veröffentlicht in:Journal of vascular surgery 2016-02, Vol.63 (2), p.323-331.e1
Hauptverfasser: Benrashid, Ehsan, MD, Wang, Hanghang, MD, Keenan, Jeffrey E., MD, Andersen, Nicholas D., MD, Meza, James M., MD, McCann, Richard L., MD, Hughes, G. Chad, MD
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container_end_page 331.e1
container_issue 2
container_start_page 323
container_title Journal of vascular surgery
container_volume 63
creator Benrashid, Ehsan, MD
Wang, Hanghang, MD
Keenan, Jeffrey E., MD
Andersen, Nicholas D., MD
Meza, James M., MD
McCann, Richard L., MD
Hughes, G. Chad, MD
description Objective The role of hybrid repair in the management of aortic arch pathology, and long-term outcomes with these techniques, remains uncertain. We report a decade of experience with hybrid arch repair (HAR) and assess institutional practice patterns with regard to the use of hybrid and open techniques. Methods Hybrid and open total and distal arch procedures performed between July 2005 and January 2015 were identified from a prospectively maintained, institutional aortic surgery database. Perioperative morbidity and mortality, freedom from reintervention, and long-term survival were calculated. Hybrid and open procedural volumes over the study period were assessed to evaluate for potential practice pattern changes. Results During the study period 148 consecutive procedures were performed for repair of transverse and distal aortic arch pathology, including 101 hybrid repairs and 47 open total or distal arch repairs. Patients in the hybrid repair group were significantly older with a greater incidence of chronic kidney disease, peripheral vascular disease, and chronic lung disease. Perioperative mortality and outcomes were not significantly different between the hybrid and open groups, aside from decreased median length of stay after hybrid repair. Need for subsequent reintervention was significantly greater after hybrid repair. Unadjusted long-term survival was superior after open repair (70% 5-year survival open vs 47% hybrid; P  = .03), although aorta-specific survival was similar (98% 5-year aorta-specific survival open vs 93% hybrid; P  = .59). Institutional use of HAR decreased over the final 3 years of the study, with an associated increased use of open total or distal arch repairs. This was primarily the result of decreased use of native zone 0 hybrid procedures. Concurrent with this apparent increased stringency around patient selection for HAR, perioperative morbidity and mortality was reduced, including avoidance of retrograde type A dissection. Conclusions HAR remains a viable option for higher-risk patients with transverse arch pathology with perioperative outcomes and long-term aorta-specific survival similar to open repair, albeit at a cost of increased reintervention. This observational single-institution study would suggest decreased use in more recent years in favor of open repair due to avoidance of native zone 0 hybrid procedures. This decline in the institutional use of native zone 0 hybrid repairs was associated with improved periopera
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Chad, MD</creator><creatorcontrib>Benrashid, Ehsan, MD ; Wang, Hanghang, MD ; Keenan, Jeffrey E., MD ; Andersen, Nicholas D., MD ; Meza, James M., MD ; McCann, Richard L., MD ; Hughes, G. Chad, MD</creatorcontrib><description>Objective The role of hybrid repair in the management of aortic arch pathology, and long-term outcomes with these techniques, remains uncertain. We report a decade of experience with hybrid arch repair (HAR) and assess institutional practice patterns with regard to the use of hybrid and open techniques. Methods Hybrid and open total and distal arch procedures performed between July 2005 and January 2015 were identified from a prospectively maintained, institutional aortic surgery database. Perioperative morbidity and mortality, freedom from reintervention, and long-term survival were calculated. Hybrid and open procedural volumes over the study period were assessed to evaluate for potential practice pattern changes. Results During the study period 148 consecutive procedures were performed for repair of transverse and distal aortic arch pathology, including 101 hybrid repairs and 47 open total or distal arch repairs. Patients in the hybrid repair group were significantly older with a greater incidence of chronic kidney disease, peripheral vascular disease, and chronic lung disease. Perioperative mortality and outcomes were not significantly different between the hybrid and open groups, aside from decreased median length of stay after hybrid repair. Need for subsequent reintervention was significantly greater after hybrid repair. Unadjusted long-term survival was superior after open repair (70% 5-year survival open vs 47% hybrid; P  = .03), although aorta-specific survival was similar (98% 5-year aorta-specific survival open vs 93% hybrid; P  = .59). Institutional use of HAR decreased over the final 3 years of the study, with an associated increased use of open total or distal arch repairs. This was primarily the result of decreased use of native zone 0 hybrid procedures. Concurrent with this apparent increased stringency around patient selection for HAR, perioperative morbidity and mortality was reduced, including avoidance of retrograde type A dissection. Conclusions HAR remains a viable option for higher-risk patients with transverse arch pathology with perioperative outcomes and long-term aorta-specific survival similar to open repair, albeit at a cost of increased reintervention. This observational single-institution study would suggest decreased use in more recent years in favor of open repair due to avoidance of native zone 0 hybrid procedures. This decline in the institutional use of native zone 0 hybrid repairs was associated with improved perioperative outcomes.</description><identifier>ISSN: 0741-5214</identifier><identifier>EISSN: 1097-6809</identifier><identifier>DOI: 10.1016/j.jvs.2015.09.004</identifier><identifier>PMID: 26518097</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Aged ; Aorta, Thoracic - surgery ; Aortic Diseases - diagnosis ; Aortic Diseases - mortality ; Aortic Diseases - surgery ; Blood Vessel Prosthesis Implantation - adverse effects ; Blood Vessel Prosthesis Implantation - mortality ; Blood Vessel Prosthesis Implantation - trends ; Databases, Factual ; Disease-Free Survival ; Endovascular Procedures - adverse effects ; Endovascular Procedures - mortality ; Endovascular Procedures - trends ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; North Carolina ; Patient Selection ; Postoperative Complications - mortality ; Postoperative Complications - therapy ; Practice Patterns, Physicians' - trends ; Retreatment ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Surgery ; Time Factors ; Treatment Outcome</subject><ispartof>Journal of vascular surgery, 2016-02, Vol.63 (2), p.323-331.e1</ispartof><rights>Society for Vascular Surgery</rights><rights>2016 Society for Vascular Surgery</rights><rights>Copyright © 2016 Society for Vascular Surgery. Published by Elsevier Inc. 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Chad, MD</creatorcontrib><title>Evolving practice pattern changes and outcomes in the era of hybrid aortic arch repair</title><title>Journal of vascular surgery</title><addtitle>J Vasc Surg</addtitle><description>Objective The role of hybrid repair in the management of aortic arch pathology, and long-term outcomes with these techniques, remains uncertain. We report a decade of experience with hybrid arch repair (HAR) and assess institutional practice patterns with regard to the use of hybrid and open techniques. Methods Hybrid and open total and distal arch procedures performed between July 2005 and January 2015 were identified from a prospectively maintained, institutional aortic surgery database. Perioperative morbidity and mortality, freedom from reintervention, and long-term survival were calculated. Hybrid and open procedural volumes over the study period were assessed to evaluate for potential practice pattern changes. Results During the study period 148 consecutive procedures were performed for repair of transverse and distal aortic arch pathology, including 101 hybrid repairs and 47 open total or distal arch repairs. Patients in the hybrid repair group were significantly older with a greater incidence of chronic kidney disease, peripheral vascular disease, and chronic lung disease. Perioperative mortality and outcomes were not significantly different between the hybrid and open groups, aside from decreased median length of stay after hybrid repair. Need for subsequent reintervention was significantly greater after hybrid repair. Unadjusted long-term survival was superior after open repair (70% 5-year survival open vs 47% hybrid; P  = .03), although aorta-specific survival was similar (98% 5-year aorta-specific survival open vs 93% hybrid; P  = .59). Institutional use of HAR decreased over the final 3 years of the study, with an associated increased use of open total or distal arch repairs. This was primarily the result of decreased use of native zone 0 hybrid procedures. Concurrent with this apparent increased stringency around patient selection for HAR, perioperative morbidity and mortality was reduced, including avoidance of retrograde type A dissection. Conclusions HAR remains a viable option for higher-risk patients with transverse arch pathology with perioperative outcomes and long-term aorta-specific survival similar to open repair, albeit at a cost of increased reintervention. This observational single-institution study would suggest decreased use in more recent years in favor of open repair due to avoidance of native zone 0 hybrid procedures. 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Chad, MD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of vascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Benrashid, Ehsan, MD</au><au>Wang, Hanghang, MD</au><au>Keenan, Jeffrey E., MD</au><au>Andersen, Nicholas D., MD</au><au>Meza, James M., MD</au><au>McCann, Richard L., MD</au><au>Hughes, G. Chad, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evolving practice pattern changes and outcomes in the era of hybrid aortic arch repair</atitle><jtitle>Journal of vascular surgery</jtitle><addtitle>J Vasc Surg</addtitle><date>2016-02-01</date><risdate>2016</risdate><volume>63</volume><issue>2</issue><spage>323</spage><epage>331.e1</epage><pages>323-331.e1</pages><issn>0741-5214</issn><eissn>1097-6809</eissn><abstract>Objective The role of hybrid repair in the management of aortic arch pathology, and long-term outcomes with these techniques, remains uncertain. We report a decade of experience with hybrid arch repair (HAR) and assess institutional practice patterns with regard to the use of hybrid and open techniques. Methods Hybrid and open total and distal arch procedures performed between July 2005 and January 2015 were identified from a prospectively maintained, institutional aortic surgery database. Perioperative morbidity and mortality, freedom from reintervention, and long-term survival were calculated. Hybrid and open procedural volumes over the study period were assessed to evaluate for potential practice pattern changes. Results During the study period 148 consecutive procedures were performed for repair of transverse and distal aortic arch pathology, including 101 hybrid repairs and 47 open total or distal arch repairs. Patients in the hybrid repair group were significantly older with a greater incidence of chronic kidney disease, peripheral vascular disease, and chronic lung disease. Perioperative mortality and outcomes were not significantly different between the hybrid and open groups, aside from decreased median length of stay after hybrid repair. Need for subsequent reintervention was significantly greater after hybrid repair. Unadjusted long-term survival was superior after open repair (70% 5-year survival open vs 47% hybrid; P  = .03), although aorta-specific survival was similar (98% 5-year aorta-specific survival open vs 93% hybrid; P  = .59). Institutional use of HAR decreased over the final 3 years of the study, with an associated increased use of open total or distal arch repairs. This was primarily the result of decreased use of native zone 0 hybrid procedures. Concurrent with this apparent increased stringency around patient selection for HAR, perioperative morbidity and mortality was reduced, including avoidance of retrograde type A dissection. Conclusions HAR remains a viable option for higher-risk patients with transverse arch pathology with perioperative outcomes and long-term aorta-specific survival similar to open repair, albeit at a cost of increased reintervention. This observational single-institution study would suggest decreased use in more recent years in favor of open repair due to avoidance of native zone 0 hybrid procedures. This decline in the institutional use of native zone 0 hybrid repairs was associated with improved perioperative outcomes.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26518097</pmid><doi>10.1016/j.jvs.2015.09.004</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
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subjects Adult
Aged
Aorta, Thoracic - surgery
Aortic Diseases - diagnosis
Aortic Diseases - mortality
Aortic Diseases - surgery
Blood Vessel Prosthesis Implantation - adverse effects
Blood Vessel Prosthesis Implantation - mortality
Blood Vessel Prosthesis Implantation - trends
Databases, Factual
Disease-Free Survival
Endovascular Procedures - adverse effects
Endovascular Procedures - mortality
Endovascular Procedures - trends
Female
Humans
Kaplan-Meier Estimate
Male
Middle Aged
North Carolina
Patient Selection
Postoperative Complications - mortality
Postoperative Complications - therapy
Practice Patterns, Physicians' - trends
Retreatment
Retrospective Studies
Risk Assessment
Risk Factors
Surgery
Time Factors
Treatment Outcome
title Evolving practice pattern changes and outcomes in the era of hybrid aortic arch repair
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