γ-H2AX/53BP1/pKAP-1 foci and their linear tracks induced by in vitro exposure to radon and its progeny in human peripheral blood lymphocytes

The biodosimetric information is critical for evaluating the human health hazards caused by radon and its progeny. Here, we demonstrated that the formation of phosphorylated histone variant H2AX (γ-H2AX), p53-binding protein 1 (53BP1) and phosphorylated KRAB-associated protein 1 (pKAP-1) foci and th...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2016-12, Vol.6 (1), p.38295-38295, Article 38295
Hauptverfasser:	Ding, Defang, Zhang, Yaping, Wang, Jing, Wang, Xufei, Fan, Dunhuang, He, Linfeng, Zhang, Xuxia, Gao, Yun, Li, Qiang, Chen, Honghong
Format:	Artikel
Sprache:	eng
Schlagworte:	13 13/51 692/1537 692/53/2423 Air Pollutants, Radioactive - pharmacology DNA - genetics DNA - metabolism DNA Breaks, Double-Stranded DNA Repair Dose-Response Relationship, Radiation Histones - genetics Histones - metabolism Humanities and Social Sciences Humans Leukocytes, Mononuclear - metabolism Leukocytes, Mononuclear - radiation effects multidisciplinary Phosphorylation - radiation effects Primary Cell Culture Radiometry Radon - pharmacology Science Tripartite Motif-Containing Protein 28 - genetics Tripartite Motif-Containing Protein 28 - metabolism Tumor Suppressor p53-Binding Protein 1 - genetics Tumor Suppressor p53-Binding Protein 1 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!