Dissecting relative contributions of cis- and trans-determinants to nucleosome distribution by comparing Tetrahymena macronuclear and micronuclear chromatin

The ciliate protozoan Tetrahymena thermophila contains two types of structurally and functionally differentiated nuclei: the transcriptionally active somatic macronucleus (MAC) and the transcriptionally silent germ-line micronucleus (MIC). Here, we demonstrate that MAC features well-positioned nucle...

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Veröffentlicht in:	Nucleic acids research 2016-12, Vol.44 (21), p.10091-10105
Hauptverfasser:	Xiong, Jie, Gao, Shan, Dui, Wen, Yang, Wentao, Chen, Xiao, Taverna, Sean D, Pearlman, Ronald E, Ashlock, Wendy, Miao, Wei, Liu, Yifan
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatin - genetics Chromatin - metabolism DNA Polymerase II - genetics DNA Polymerase II - metabolism Gene regulation, Chromatin and Epigenetics Macronucleus - genetics Macronucleus - metabolism Micrococcal Nuclease - genetics Micrococcal Nuclease - metabolism Micronucleus, Germline - genetics Nucleosomes - genetics Nucleosomes - metabolism RNA Splice Sites Tetrahymena thermophila - genetics Transcription Initiation Site
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