The N14 anti-afamin antibody Fab: a rare VL1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling

The monoclonal antibody N14 is used as a detection antibody in ELISA kits for the human glycoprotein afamin, a member of the albumin family, which has recently gained interest in the capture and stabilization of Wnt signalling proteins, and for its role in metabolic syndrome and papillary thyroid ca...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Acta crystallographica. Section D, Biological crystallography. Biological crystallography., 2016-12, Vol.72 (12), p.1267-1280
Hauptverfasser:	Naschberger, Andreas, Fürnrohr, Barbara G., Lenac Rovis, Tihana, Malic, Suzana, Scheffzek, Klaus, Dieplinger, Hans, Rupp, Bernhard
Format:	Artikel
Sprache:	eng
Schlagworte:	accuracy antibody fragment elbow angle flexibility non-apparent isomorphism precision Research Papers solvent solvent modelling variable-chain glycosylation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!