Tonsil-Derived Mesenchymal Stem Cells Differentiate into a Schwann Cell Phenotype and Promote Peripheral Nerve Regeneration

Schwann cells (SCs), which produce neurotropic factors and adhesive molecules, have been reported previously to contribute to structural support and guidance during axonal regeneration; therefore, they are potentially a crucial target in the restoration of injured nervous tissues. Autologous SC tran...

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Veröffentlicht in:	International journal of molecular sciences 2016-11, Vol.17 (11), p.1867-1867
Hauptverfasser:	Jung, Namhee, Park, Saeyoung, Choi, Yoonyoung, Park, Joo-Won, Hong, Young Bin, Park, Hyun Ho Choi, Yu, Yeonsil, Kwak, Geon, Kim, Han Su, Ryu, Kyung-Ha, Kim, Jae Kwang, Jo, Inho, Choi, Byung-Ok, Jung, Sung-Chul
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers - metabolism Cell Differentiation Cell growth Child Coculture Techniques Ganglia, Spinal - cytology Ganglia, Spinal - metabolism Gene Expression Humans Male Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - metabolism Mice Mice, Inbred C57BL Nerve Regeneration - physiology Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Nervous system Neurons Neurons - cytology Neurons - metabolism Palatine Tonsil - cytology Palatine Tonsil - metabolism Palatine Tonsil - surgery Peripheral Nerve Injuries - metabolism Peripheral Nerve Injuries - pathology Peripheral Nerve Injuries - rehabilitation Peripheral Nerve Injuries - surgery Recovery of Function Schwann Cells - cytology Schwann Cells - metabolism Schwann Cells - transplantation Sciatic Nerve - injuries Sciatic Nerve - metabolism Stem cells Throat Tonsillectomy Transplantation, Heterologous
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