Buprenorphine compared with methadone to treat pregnant women with opioid use disorder: a systematic review and meta-analysis of safety in the mother, fetus and child

Aims To assess the safety of buprenorphine compared with methadone to treat pregnant women with opioid use disorder. Methods We searched PubMed, Embase and the Cochrane Library from inception to February 2015 for randomized controlled trials (RCT) and observational cohort studies (OBS) that compared...

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Veröffentlicht in:	Addiction (Abingdon, England) England), 2016-12, Vol.111 (12), p.2115-2128
Hauptverfasser:	Zedler, Barbara K., Mann, Ashley L., Kim, Mimi M., Amick, Halle R., Joyce, Andrew R., Murrelle, E. Lenn, Jones, Hendrée E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Drug-Induced - prevention & control Analgesics, Opioid - therapeutic use Birth Weight - physiology Buprenorphine Buprenorphine - therapeutic use dependence Drug addiction Female Fetal Death - prevention & control Fetal Development - drug effects fetus harm Humans Infant, Newborn Meta-analysis Methadone Methadone - therapeutic use Narcotics Opiate Substitution Treatment - methods opioid use disorder Opioid-Related Disorders - rehabilitation Patient Safety Pregnancy Pregnancy Complications - rehabilitation Pregnancy Outcome Premature Birth - prevention & control Prenatal Care - methods Randomized Controlled Trials as Topic Review Reviews Sudden Infant Death - prevention & control Systematic review
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