Quantitative determination of ribosome nascent chain stability

Accurate protein folding is essential for proper cellular and organismal function. In the cell, protein folding is carefully regulated; changes in folding homeostasis (proteostasis) can disrupt many cellular processes and have been implicated in various neurodegenerative diseases and other pathologi...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2016-11, Vol.113 (47), p.13402-13407
Hauptverfasser: Samelson, Avi J., Jensen, Madeleine K., Soto, Randy A., Cate, Jamie H. D., Marqusee, Susan
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Sprache:eng
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