Identification of ITGA2B and ITGB3 Single-Nucleotide Polymorphisms and Their Influences on the Platelet Function

The aim of the study was to investigate ITGA2B and ITGB3 genetic polymorphisms and to evaluate the variability in the platelet function in healthy Chinese subjects. The genetic sequence of the entire coding region of the ITGA2B and ITGB3 genes was investigated. Adenosine diphosphate-induced platelet...

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Veröffentlicht in:	BioMed research international 2016-01, Vol.2016 (2016), p.1-11
Hauptverfasser:	Zhao, Xia, Zhang, Zhuo, Ji, Shun-Dong, Xiang, Qian, Cui, Yi-Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute coronary syndromes Adenosine triphosphatase Adolescent Adult Alleles Asian Continental Ancestry Group - genetics Bleeding Time - methods Blood Blood Coagulation - genetics Blood coagulation factors Blood platelets Blood Platelets - physiology Cardiovascular disease Ethnicity Family medical history Fibrin Fibrinogen - genetics Genetic aspects Genotype Hematology Humans Integrin alpha2 - genetics Integrin beta3 - genetics Laboratories Mean Platelet Volume - methods Medical examination Middle Aged Open Reading Frames - genetics Platelet Aggregation - genetics Polymorphism, Single Nucleotide - genetics Prothrombin Time - methods Single nucleotide polymorphisms Studies Thrombosis Young Adult
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