Atg1‐independent induction of autophagy by the Drosophila Ulk3 homolog, ADUK

Although canonical autophagy regulation requires a multi‐protein complex centered on the Ser/Thr‐kinase Atg1 (mammalian Ulk1/2), alternative signals can induce autophagy independent of Atg1 through unknown mechanisms. Here we identify the Drosophila Ulk3 ortholog, another Drosophila Unc‐51‐like kina...

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Veröffentlicht in:	The FEBS journal 2016-11, Vol.283 (21), p.3889-3897
Hauptverfasser:	Braden, Christopher R., Neufeld, Thomas P.
Format:	Artikel
Sprache:	eng
Schlagworte:	adults Amino Acid Sequence Animals Animals, Genetically Modified Atg1 Autophagy Autophagy-Related Protein-1 Homolog - classification Autophagy-Related Protein-1 Homolog - genetics Autophagy-Related Protein-1 Homolog - metabolism Autophagy-Related Proteins - genetics Autophagy-Related Proteins - metabolism Base Sequence Blotting, Western dimethyl sulfoxide Drosophila Drosophila Proteins - classification Drosophila Proteins - genetics Drosophila Proteins - metabolism Female Insects Kinases longevity Male mammals Microscopy, Confocal Mutation Phylogeny Protein Binding Protein-Serine-Threonine Kinases - classification Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Proteins Signal Transduction Ulk1 Ulk3
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