MARCKS contributes to stromal cancer-associated fibroblast activation and facilitates ovarian cancer metastasis

The Cancer Genome Atlas network has revealed that the 'mesenchymal' epithelial ovarian cancer (EOC) subtype represents the poorest outcome, indicating a crucial role of stromal cancer-associated fibroblasts (CAFs) in disease progression. The cooperative role of CAFs in EOC metastasis has l...

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Veröffentlicht in:	Oncotarget 2016-06, Vol.7 (25), p.37649-37663
Hauptverfasser:	Yang, Zongyuan, Xu, Sen, Jin, Ping, Yang, Xin, Li, Xiaoting, Wan, Dongyi, Zhang, Taoran, Long, Sixiang, Wei, Xiao, Chen, Gang, Meng, Li, Liu, Dan, Fang, Yong, Chen, Pingbo, Ma, Ding, Gao, Qinglei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer-Associated Fibroblasts - metabolism Cancer-Associated Fibroblasts - pathology Cell Differentiation - physiology Cell Line, Tumor Disease-Free Survival Female Humans Mice Myristoylated Alanine-Rich C Kinase Substrate - genetics Myristoylated Alanine-Rich C Kinase Substrate - metabolism Neoplasm Metastasis Ovarian Neoplasms - genetics Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology Research Paper Signal Transduction
Online-Zugang:	Volltext
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