Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infection Control in an Institutional Setting

The increasing prevalence of multidrug-resistant (MDR) bacteria is a serious global challenge. Here, we studied prospectively whether bacterial whole-genome sequencing (WGS) for real-time MDR surveillance is technical feasible, returns actionable results, and is cost-beneficial. WGS was applied to a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical microbiology 2016-12, Vol.54 (12), p.2874-2881
Hauptverfasser:	Mellmann, Alexander, Bletz, Stefan, Böking, Thomas, Kipp, Frank, Becker, Karsten, Schultes, Anja, Prior, Karola, Harmsen, Dag
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacteriology Cefotaxime - pharmacology Ciprofloxacin - pharmacology Cross Infection - microbiology Cross Infection - transmission Enterococcus faecium - drug effects Enterococcus faecium - genetics Enterococcus faecium - isolation & purification Escherichia coli - drug effects Escherichia coli - genetics Escherichia coli - isolation & purification Escherichia coli Infections - transmission Genome, Bacterial - genetics Gram-Positive Bacterial Infections - transmission High-Throughput Nucleotide Sequencing Humans Infection Control - methods Methicillin-Resistant Staphylococcus aureus - drug effects Methicillin-Resistant Staphylococcus aureus - genetics Methicillin-Resistant Staphylococcus aureus - isolation & purification Microbial Sensitivity Tests Piperacillin - pharmacology Prospective Studies Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - genetics Pseudomonas aeruginosa - isolation & purification Pseudomonas Infections - transmission Sequence Analysis, DNA Staphylococcal Infections - transmission Vancomycin-Resistant Enterococci - drug effects Vancomycin-Resistant Enterococci - genetics Vancomycin-Resistant Enterococci - isolation & purification
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!