DDIT4 regulates mesenchymal stem cell fate by mediating between HIF1α and mTOR signalling

Stem cell fate decisions to remain quiescent, self-renew or differentiate are largely governed by the interplay between extracellular signals from the niche and the cell intrinsic signal cascades and transcriptional programs. Here we demonstrate that DNA Damage Inducible Transcript 4 (DDIT4) acts as...

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Veröffentlicht in:	Scientific reports 2016-11, Vol.6 (1), p.36889-36889, Article 36889
Hauptverfasser:	Gharibi, Borzo, Ghuman, Mandeep, Hughes, Francis J.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/100 13/106 38 38/77 631/532/2074 631/532/2441 Humanities and Social Sciences multidisciplinary Science
Online-Zugang:	Volltext
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