Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid

With their essential role in inner ear function, stereocilia of sensory hair cells demonstrate the importance of cellular actin protrusions. Actin packing in stereocilia is mediated by cross-linkers of the plastin, fascin, and espin families. Although mice lacking espin (ESPN) have no vestibular or...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of cell biology 2016-11, Vol.215 (4), p.467-482
Hauptverfasser:	Krey, Jocelyn F, Krystofiak, Evan S, Dumont, Rachel A, Vijayakumar, Sarath, Choi, Dongseok, Rivero, Francisco, Kachar, Bechara, Jones, Sherri M, Barr-Gillespie, Peter G
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - metabolism Animals Biochemistry Carrier Proteins - genetics Cellular biology Cross-Linking Reagents - metabolism Ears & hearing Hair Cells, Auditory - metabolism Hair Cells, Auditory - ultrastructure Mass spectrometry Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Mice, Inbred C57BL Microfilament Proteins - genetics Microfilament Proteins - metabolism Mutation - genetics Proteins Proteomics Rodents Saccule and Utricle - metabolism Saccule and Utricle - physiopathology Saccule and Utricle - ultrastructure Sensory perception Stereocilia - metabolism Stereocilia - ultrastructure Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!