Treatment with Cestode Parasite Antigens Results in Recruitment of CCR2+ Myeloid Cells, the Adoptive Transfer of Which Ameliorates Colitis

Awareness of the immunological underpinnings of host-parasite interactions may reveal immune signaling pathways that could be used to treat inflammatory disease in humans. Previously we showed that infection with the rat tapeworm, Hymenolepis diminuta, used as a model helminth, or systemic delivery...

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Veröffentlicht in:	Infection and immunity 2016-12, Vol.84 (12), p.3471-3483
Hauptverfasser:	Reyes, José L, Lopes, Fernando, Leung, Gabriella, Mancini, Nicole L, Matisz, Chelsea E, Wang, Arthur, Thomson, Emma A, Graves, Nicholas, Gilleard, John, McKay, Derek M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer Animals Antigens, Helminth CD4-Positive T-Lymphocytes Colitis - chemically induced Cytokines - genetics Cytokines - metabolism Dextran Sulfate - toxicity Gene Expression Regulation Host Response and Inflammation Hymenolepis diminuta - metabolism Male Mice Mice, Inbred BALB C Mice, Inbred C57BL Monocytes - metabolism Myeloid Cells - physiology
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