Expression of Par3 polarity protein correlates with poor prognosis in ovarian cancer

Previous studies have shown that the cell polarity protein partitioning defective 3 (Par3) plays an essential role in the formation of tight junctions and definition of apical-basal polarity. Aberrant function of this protein has been reported to be involved in epithelial-mesenchymal transition (EMT...

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Veröffentlicht in:	BMC cancer 2016-11, Vol.16 (1), p.897-897, Article 897
Hauptverfasser:	Nakamura, Hiroe, Nagasaka, Kazunori, Kawana, Kei, Taguchi, Ayumi, Uehara, Yuriko, Yoshida, Mitsuyo, Sato, Masakazu, Nishida, Haruka, Fujimoto, Asaha, Inoue, Tomoko, Adachi, Katsuyuki, Nagamatsu, Takeshi, Arimoto, Takahide, Oda, Katsutoshi, Osuga, Yutaka, Fujii, Tomoyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing Adult Aged Aged, 80 and over Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cell Line, Tumor Cell Proliferation Complications and side effects Development and progression Female Gene Expression Profiling - methods Gene Expression Regulation, Neoplastic Humans Interleukin-6 - genetics Interleukin-6 - metabolism Membrane Proteins - genetics Membrane Proteins - metabolism Metastasis Middle Aged Neoplasm Invasiveness Oligonucleotide Array Sequence Analysis - methods Ovarian cancer Ovarian Neoplasms - genetics Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology Peritoneal Neoplasms - genetics Peritoneal Neoplasms - metabolism Peritoneal Neoplasms - secondary Prognosis Risk factors Signal Transduction STAT3 Transcription Factor - metabolism Stem cell research Survival Analysis
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