Association of change in brain structure to objectively measured physical activity and sedentary behavior in older adults: Age, Gene/Environment Susceptibility-Reykjavik Study

•Accelerometer was used to measure physical activity and sedentary behavior at follow up.•Gray matter and white matter was measured both at baseline and follow up, with 5-year interval.•An association was found between brain atrophy and physical activity.•There was also an association between brain...

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