Enterovirus 71 infection of motor neuron-like NSC-34 cells undergoes a non-lytic exit pathway

Enterovirus 71 (EV71) causing Hand, Foot and Mouth Disease, is regarded as the most important neurotropic virus worldwide. EV71 is believed to replicate in muscles and infect motor neurons to reach the central nervous system (CNS). To further investigate the mechanisms involved, we have employed the...

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Veröffentlicht in:	Scientific reports 2016-11, Vol.6 (1), p.36983-36983, Article 36983
Hauptverfasser:	Too, Issac Horng Khit, Yeo, Huimin, Sessions, October Michael, Yan, Benedict, Libau, Eshele Anak, Howe, Josephine L. C., Lim, Ze Qin, Suku-Maran, Shalini, Ong, Wei-Yi, Chua, Kaw Bing, Wong, Boon Seng, Chow, Vincent T. K., Alonso, Sylvie
Format:	Artikel
Sprache:	eng
Schlagworte:	13 13/1 13/109 13/2 13/31 13/51 14 14/19 14/28 631/326/596/2555 631/80/82 82 82/29 Apoptosis Autophagy Cell culture Cell Line Cell lines Central nervous system Enterovirus A, Human - physiology Hand-foot-and-mouth disease Humanities and Social Sciences Humans Infections Laboratories Life sciences Medicine Motor neurons Motor Neurons - physiology Motor Neurons - virology Motor task performance multidisciplinary Muscles Nervous system Neuroblastoma Neurons Neurovirulence Phagocytosis Proteins Science Spinal cord Vacuoles Virus Cultivation Virus Internalization Virus Release Virus Replication
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