Opening the Channel: the Two Functional Interfaces of Pseudomonas aeruginosa OpmH with the Triclosan Efflux Pump TriABC

TriABC-OpmH is an efflux pump from Pseudomonas aeruginosa with an unusual substrate specificity and protein composition. When overexpressed, this pump confers a high level of resistance to the biocide triclosan and the detergent SDS, which are commonly used in combinations for antimicrobial treatmen...

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Veröffentlicht in:	Journal of bacteriology 2016-12, Vol.198 (23), p.3176-3185
Hauptverfasser:	Ntreh, Abigail T, Weeks, Jon W, Nickels, Logan M, Zgurskaya, Helen I
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - metabolism Antimicrobial agents Bacteria Bacteriology Biocides Biological Transport Membrane Transport Proteins - genetics Membrane Transport Proteins - metabolism Membranes Microbiology Proteins Pseudomonas aeruginosa - genetics Pseudomonas aeruginosa - metabolism Spotlight Triclosan - metabolism
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