A simple method to improve the stability of docetaxel micelles

Self-assembled polymeric micelles have been widely applied in drug delivery systems. In this study, we found that pH value of micellar system solution was the decisive factor of physical stability. Furthermore, the weak basic solution could maintain the solution clarification for a relative long tim...

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Veröffentlicht in:	Scientific reports 2016-11, Vol.6 (1), p.36957, Article 36957
Hauptverfasser:	Zhang, Lan, Tan, LiWei, Chen, LiJuan, Chen, XiaoXin, Long, ChaoFeng, Peng, JinRong, Qian, ZhiYong
Format:	Artikel
Sprache:	eng
Schlagworte:	140/131 631/154/152 692/308/153 Antitumor activity Antitumor agents Breast cancer Clinical trials Controlled release Drug delivery Drug delivery systems Drugs Freeze drying Humanities and Social Sciences Lung cancer Micelles multidisciplinary Particle size pH effects Polymers Powder Science Therapeutic applications Toxicity
Online-Zugang:	Volltext
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