miR-24-3p Regulates Progression of Gastric Mucosal Lesions and Suppresses Proliferation and Invasiveness of N87 Via Peroxiredoxin 6

Background MicroRNAs, targeting mRNAs of cancer-associated genes, are often aberrantly expressed in human gastric cancer (GC). Aim We have examined the possible role and mechanisms of miRNA regulation of Prdx-6 in the development and progression of H. pylori -related gastric mucosal lesions. Methods...

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Veröffentlicht in:	Digestive diseases and sciences 2016-12, Vol.61 (12), p.3486-3497
Hauptverfasser:	Li, Qian, Wang, Nina, Wei, Hong, Li, Chao, Wu, Jing, Yang, Guibin
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apoptosis - genetics Biochemistry Blotting, Western Cancer Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Development and progression Down-Regulation Gastric Mucosa Gastritis - genetics Gastritis - metabolism Gastritis - pathology Gastroenterology Gene Expression Regulation, Neoplastic Genes Genetic aspects Health aspects Helicobacter infections Helicobacter Infections - genetics Helicobacter Infections - metabolism Helicobacter Infections - pathology Helicobacter pylori Hepatology Humans Immunohistochemistry In Situ Hybridization Liver cancer Medicine Medicine & Public Health MicroRNA MicroRNAs - genetics Neoplasm Invasiveness Oncology Original Original Article Peroxiredoxin VI - genetics Peroxiredoxin VI - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Stomach cancer Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Transplant Surgery Up-Regulation
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