MDM2 antagonist clinical response association with a gene expression signature in acute myeloid leukaemia

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Veröffentlicht in:	British journal of haematology 2015-11, Vol.171 (3), p.432-435
Hauptverfasser:	Zhong, Hua, Chen, Gong, Jukofsky, Lori, Geho, David, Han, Sung Won, Birzele, Fabian, Bader, Sabine, Himmelein, Lucia, Cai, James, Albertyn, Zayed, Rothe, Mark, Essioux, Laurent, Burtscher, Helmut, Middleton, Steven A., Rueger, Ruediger, Chen, Lin‐Chi, Dangl, Markus, Nichols, Gwen, Pierceall, William E.
Format:	Artikel
Sprache:	eng
Schlagworte:	acute myeloid leukaemia Adult Aged Cell Line, Tumor diagnostic algorithm Female Gene Expression Profiling Gene Expression Regulation, Leukemic - drug effects gene expression signature Humans Imidazolines - administration & dosage Imidazolines - adverse effects Leukemia, Myeloid, Acute - drug therapy Leukemia, Myeloid, Acute - enzymology Male MDM2 antagonist Middle Aged Proto-Oncogene Proteins c-mdm2 - antagonists & inhibitors Proto-Oncogene Proteins c-mdm2 - metabolism TP53
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