Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma

Cytokines produced in the tumour microenvironment exert an important role in cancer pathogenesis and in the inhibition of disease progression. Cancer of the cartilage is termed metastatic chondrosarcoma; however, the signaling events resulting in mesenchymal cell transformation to sarcoma have yet t...

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Veröffentlicht in:	Molecular and clinical oncology 2016-11, Vol.5 (5), p.618-624
Hauptverfasser:	Galoian, Karina, Luo, Shihua, Qureshi, Amir, Patel, Parthik, Price, Rachel, Morse, Ashlyn S, Chailyan, Gor, Abrahamyan, Silva, Temple, H. T
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cellular signal transduction Chondrosarcoma Cytokines Development and progression Enzymes Gene expression Genetic aspects Growth factors Health aspects Immunoglobulins Inflammation interleukin-6 Laboratories Membranes Oncology Penicillin Polypeptides proline-rich polypeptide-1 Properties Proteins suppressor of cytokine signaling 3 Tumor necrosis factor-TNF Tumors
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